Hello, Sushmita.

If you are using the command line liftOver tool to convert mm9 genomic
coordinates to mm10 genomic coordinates, then yes, you will use that file to
perform the conversion.  The basic usage of the liftOver tool is as follows:

liftOver oldfile map.chain newfile unmapped

oldfile: The file that contains your list of mm9 coordinates
map.chain: The mm9ToMm10.over.chain file that you downloaded
newfile: A target file that will contain the equivalent mm10 coordinates
unMapped: A target file that contains any coordinates that could not be
lifted over

Please note that there is also a web-based liftOver tool that performs the
same function and does not require you to download additional files.  The
web-based liftOver tool is located at
http://genome.ucsc.edu/cgi-bin/hgLiftOver.

Please contact us again at [email protected] if you have any further
questions.

---
Steve Heitner
UCSC Genome Bioinformatics Group

-----Original Message-----
From: [email protected] [mailto:[email protected]] On
Behalf Of sushmita
Sent: Wednesday, June 20, 2012 5:26 AM
To: [email protected]
Subject: [Genome] Query related to liftOver tool

Dear Sir/Madam,

I downloaded "mm9ToMm10.over.chain" file from UCSC site. But the file
content is not clear to me. Can you please help me to understand that? 
Shall I use this file to run "liftOver" tool?

Thanks and Regards,

Sushmita
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