editconf option,-f input.gro -o output.gro -bt triclinic -box 4 4 6
is not recommended for a box size of size is 3,2,6 in x,y,z
use -d 0.0 instead of -box 4 4 6
Read about it here:
http://www.gromacs.org/documentation/reference/online/editconf.html

I am assuming that you are using periodic boundary conditions and pressure scaling. In that case -box 4 4 6 will probably be fine, but be sure to visualize your system (you could use VMD). If you are unsure about periodicity (Tsjerk recently pointed out that what looks incorrect may in fact be correct) then I urge you to turn on the periodic representation in VMD and look at the system in this manner.

Chris.

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