Chih-Ying Lin wrote:



Hi
Is the time scale of the protein domain motion within nano-second?


Not typically, these motions usually occur more on the time scale of a microsecond (or more). It will depend on how large the protein is, and what amplitude the motion is, though, so I suppose anything is possible. Domain motions are more often analyzed by normal mode analysis or elastic network models, because typical solution MD doesn't achieve the appropriate time scale.

-Justin

Thank you
Lin




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Justin A. Lemkul
Ph.D. Candidate
ICTAS Doctoral Scholar
Department of Biochemistry
Virginia Tech
Blacksburg, VA
jalemkul[at]vt.edu | (540) 231-9080
http://www.bevanlab.biochem.vt.edu/Pages/Personal/justin

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