On 9/21/12 10:49 AM, Hossein Lanjanian wrote:
Dear all
I want to simulate insulin receptor in plasma membrane. The monomer form of
receptor, that has 1382 amino acid, is available in Uniprot database. But I
need dimer form of it.
question: How can I prepare a pdb file of dimer? Is there any better
suggestion instead of manipulating pdb file of monomer?


If there is no available structure for the dimer, then you need to produce one based on any and all available experimental evidence for how two monomers may interact.

-Justin

--
========================================

Justin A. Lemkul, Ph.D.
Research Scientist
Department of Biochemistry
Virginia Tech
Blacksburg, VA
jalemkul[at]vt.edu | (540) 231-9080
http://www.bevanlab.biochem.vt.edu/Pages/Personal/justin

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