JsInterop is just a convention, so permutations don't make sense here. Elemental2 is generated from a specification, so it does not use permutations. If you use Elemental2 you are responsible to apply polyfills in browsers that do not support the JS features you are using via elemental2. However there might be usages of permutations in other GWT code you might using, things like GWT-RPC, RequestFactory, .....
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