Switching the date would be a major burden and would not be doable here at 
UTSW.  We previously used result date, but found a large number of older result 
dates were off by months. I believe it was due to some IT process,like an 
import or something, but it was significant.  And when researchers would try to 
find a lab by result date, the date shown in the EMR was different making it 
hard to locate.

With order date, in the outpatient setting, sometimes a doctor may order a lab 
and the patient may not have it done for days.

With the PCORI CDM,  we are currently only using have the specimen date, 
however we plan to add the other dates.

Phillip

From: Gpc-dev 
<gpc-dev-boun...@listserv.kumc.edu<mailto:gpc-dev-boun...@listserv.kumc.edu>> 
on behalf of Al'ona Furmanchuk 
<furmanc...@icnanotox.org<mailto:furmanc...@icnanotox.org>>
Date: Wednesday, January 25, 2017 at 8:29 AM
To: Dan Connolly <dconno...@kumc.edu<mailto:dconno...@kumc.edu>>
Cc: Bernard Black 
<bbl...@kellogg.northwestern.edu<mailto:bbl...@kellogg.northwestern.edu>>, 
"<gpc-dev@listserv.kumc.edu<mailto:gpc-dev@listserv.kumc.edu>>" 
<gpc-dev@listserv.kumc.edu<mailto:gpc-dev@listserv.kumc.edu>>
Subject: Re: [gpc-informatics] #551: next-D labs for cohort selection: fasting 
glucose, HbA1c

Before we go toward changes, lets just see if we need to. I would appreciate if 
each site could fill up attached form and send back to me. I filled some sites 
based on this discussion. Please, check and correct if I got it wrong.
Alona.

On Wed, Jan 25, 2017 at 8:23 AM, Dan Connolly 
<dconno...@kumc.edu<mailto:dconno...@kumc.edu>> wrote:
Changes in HERON ETL from result date to order date or specimen date would take 
a month or two, depending on priorities. I suspect likewise at other sites.

If that sort of delay is acceptable, then I can proceed to get all 8 sites to 
resolve this deference.

On Jan 25, 2017 7:44 AM, Bernard Black 
<bbl...@kellogg.northwestern.edu<mailto:bbl...@kellogg.northwestern.edu>> wrote:

Let me chime in, as project PI.

This was a very helpful discussion.

For this study, exact dates are not important.

If blood was drawn on Tuesday, and results available on Friday,

If as I suspect (but we can check) generally order date, specimen date, and 
results date are all close, we can go with order date



Bernie Black



*************************************************************

Bernard S. Black

Chabraja Professor, Northwestern University

Pritzker Law School and Kellogg School of Management

375 East Chicago Ave., Chicago IL 60611

bbl...@northwestern.edu<mailto:bbl...@northwestern.edu>

tel:  law:  312-503-2784<tel:312-503-2784>; Kellogg 
847-491-5049<tel:847-491-5049>; cell: 847-807-9599<tel:847-807-9599>

papers on SSRN at:  http://ssrn.com/author=16042

************************************************************



From: Al'ona Furmanchuk 
[mailto:furmanc...@icnanotox.org<mailto:furmanc...@icnanotox.org>]
Sent: Wednesday, January 25, 2017 7:31 AM
To: Campbell, James R <campb...@unmc.edu<mailto:campb...@unmc.edu>>
Cc: Phillip Reeder 
<phillip.ree...@utsouthwestern.edu<mailto:phillip.ree...@utsouthwestern.edu>>; 
<gpc-dev@listserv.kumc.edu<mailto:gpc-dev@listserv.kumc.edu>> 
<gpc-dev@listserv.kumc.edu<mailto:gpc-dev@listserv.kumc.edu>>; Bernard Black 
<bbl...@kellogg.northwestern.edu<mailto:bbl...@kellogg.northwestern.edu>>
Subject: Re: [gpc-informatics] #551: next-D labs for cohort selection: fasting 
glucose, HbA1c



Guys,

Order date is important for defining study sample and DM sample. specimen date 
is important for "adherence to Treatment" variable. If difference in dates is 
minor, we could uniformly switch to specimen date. But first we have to know 
what is available in each site and ( if both dates are available) how large is 
difference between dates?

Sent from my iPhone

On Jan 24, 2017, at 10:40 PM, Campbell, James R 
<campb...@unmc.edu<mailto:campb...@unmc.edu>> wrote:

I agree with Phillip.  Clinically, the date/time reported for a lab test is 
always when the patient had blood drawn or gave the sample.  THAT is when the 
patient was 'tested'.  Nebraska records all lab test observation_facts with 
START_DATE as date/time specimen was taken.  We record order time and result 
reported time separately.

Jim

James R. Campbell MD

campb...@unmc.edu<mailto:campb...@unmc.edu>

Office: 402-559-7505<tel:(402)%20559-7505>

Secretary: 402-559-7299<tel:(402)%20559-7299>

Pager: 402-888-1230<tel:(402)%20888-1230>

On Jan 24, 2017, at 6:07 PM, Al'ona Furmanchuk 
<furmanc...@icnanotox.org<mailto:furmanc...@icnanotox.org>> wrote:

Dan: It is important to be clear what each site use under "start_date". 
Especially for cases when ORDER_DATE is different from SPECIMEN_TAKEN_DATE.

I appreciate, Dan if you could gather this info.

It is important to be on the same terms when collecting data to the table 1.

Phillip: I agree that having order, specimen and result dates is good practice. 
This is what we have here at NU as well.



Alona.





On Tue, Jan 24, 2017 at 5:49 PM, Phillip Reeder 
<phillip.ree...@utsouthwestern.edu<mailto:phillip.ree...@utsouthwestern.edu>> 
wrote:

I’d recommend using the SPECIMEN_TAKEN_DATE/TIME for the start_date of a lab.  
I believe it is the more clinically correct time as the results of labs can 
sometimes take days to return.  We use the specimen time, followed by the 
result time, I believe.



For the PCORI CDM,  I plan on putting all of the needed date/times, (specimen, 
order, and result) into a small XML block in the observation_blob column so 
that I can have all the times when I ETL the data to the CDM schema.



Phillip



From: Gpc-dev 
<gpc-dev-boun...@listserv.kumc.edu<mailto:gpc-dev-boun...@listserv.kumc.edu>> 
on behalf of Dan Connolly <dconno...@kumc.edu<mailto:dconno...@kumc.edu>>
Date: Tuesday, January 24, 2017 at 5:09 PM
To: Al'ona Furmanchuk 
<furmanc...@icnanotox.org<mailto:furmanc...@icnanotox.org>>, 
"<gpc-dev@listserv.kumc.edu<mailto:gpc-dev@listserv.kumc.edu>>" 
<gpc-dev@listserv.kumc.edu<mailto:gpc-dev@listserv.kumc.edu>>
Cc: Bernard Black <bbl...@northwestern.edu<mailto:bbl...@northwestern.edu>>
Subject: RE: [gpc-informatics] #551: next-D labs for cohort selection: fasting 
glucose, HbA1c



Reviewing the HERON ETL code, I see it does populate the i2b2 start_date for 
labs from Epic's result_time, which looks more like RESULT_DATE.

I see that our code to build the PCORNet LAB_RESULT_CM.LAB_ORDER_DATE 
(PCORNetLoader_ora.sql#L1407<https://urldefense.proofpoint.com/v2/url?u=https-3A__github.com_kumc-2Dbmi_i2p-2Dtransform_blob_cycle-5F2_Oracle_PCORNetLoader-5Fora.sql-23L1407&d=CwMFaQ&c=yHlS04HhBraes5BQ9ueu5zKhE7rtNXt_d012z2PA6ws&r=CqPxCu-EywA2wo4iO-6BFqfwPQ2roHdsnjQi7SSLgLE&m=yqG12qsoyrBif-jILwubW8btm4qM0DM258CMGa2kQBI&s=B7cCQmEWUNYYqTWtUNzSvO_w9AgOsBJBy3wEyxt_Bms&e=>)
 uses this start_date that came from result_time, so we're fudging things a bit 
there.

The HERON ETL code is used at KUMC and was the basis of work at UTHSCSA and 
UNMC. If the difference between LAB_ORDER_DATE and RESULT_DATE is significant 
for Next-D, I can find out how the other participating GPC sites do start_date 
for labs.

ref:

  *   
heron_load/epic_labs_transform.sql<https://urldefense.proofpoint.com/v2/url?u=https-3A__informatics.kumc.edu_work_browser_heron-5Fload_epic-5Flabs-5Ftransform.sql&d=CwMFaQ&c=yHlS04HhBraes5BQ9ueu5zKhE7rtNXt_d012z2PA6ws&r=CqPxCu-EywA2wo4iO-6BFqfwPQ2roHdsnjQi7SSLgLE&m=yqG12qsoyrBif-jILwubW8btm4qM0DM258CMGa2kQBI&s=pGsz33DfC6KcCqKPa98qqkrDL6z3BB6KNoYcWjFZ0F0&e=>

--
Dan

________________________________

From: Al'ona Furmanchuk 
[furmanc...@icnanotox.org<mailto:furmanc...@icnanotox.org>]
Sent: Tuesday, January 24, 2017 4:35 PM
To: <gpc-dev@listserv.kumc.edu<mailto:gpc-dev@listserv.kumc.edu>>
Cc: Mei Liu; Dan Connolly; Taylor, Bradley; Bernard Black
Subject: Re: [gpc-informatics] #551: next-D labs for cohort selection: fasting 
glucose, HbA1c

Dan,

great job!

Meanwhile, could you please clarify actual meaning of "start_date" in i2b2? Is 
it more like "LAB_OERDER_DATE" (when lab was ordered), "SPECIMEN_DATE" (when 
specimen was taken), "RESULT_DATE" (when results became available)?





Alona.



On Tue, Jan 24, 2017 at 4:06 PM, GPC Informatics 
<d...@madmode.com<mailto:d...@madmode.com>> wrote:

#551: next-D labs for cohort selection: fasting glucose, HbA1c
--------------------------+-----------------------
 Reporter:  afurmanchuk   |       Owner:  meiliu
     Type:  design-issue  |      Status:  accepted
 Priority:  major         |   Milestone:  next-d
Component:  data-stds     |  Resolution:
 Keywords:                |  Blocked By:
 Blocking:  545           |
--------------------------+-----------------------

Comment (by dconnolly):

 Alona, Mei,

 I managed to prototype using i2b2 and LOINC codes:

  - 8f27bee get FG_Intial, RG_Initial from i2b2 star schema
    
\\[https://github.com/dckc/nextd-study-<https://urldefense.proofpoint.com/v2/url?u=https-3A__github.com_dckc_nextd-2Dstudy-2D&d=CwMFaQ&c=yHlS04HhBraes5BQ9ueu5zKhE7rtNXt_d012z2PA6ws&r=CqPxCu-EywA2wo4iO-6BFqfwPQ2roHdsnjQi7SSLgLE&m=yqG12qsoyrBif-jILwubW8btm4qM0DM258CMGa2kQBI&s=pJR2npMPImLderrOyYqj8y314rhl5bxh_TdkjIazisA&e=>
 support/blob/master/NextDvariableExtractionOracleTable1GPC.sql#L138-L221
 NextDvariableExtractionOracleTable1GPC.sql lines  138-221]

 At KUMC, this results in ~500K rows in RG_Intial but 0 in FG_Intial:
 as I noted in comment:1, the LOINC code KU Hospital maps to (`Glucose
 SerPl-mCnc (2345-7)`) doesn't
 distinguish fasting from eating.

 Some changes were perhaps substantive, so I need you to evaluate the
 impact:
     - LAB_ORDER_DATE became start_date,
       which is more likely result date than order date
     - i2b2 start_date includes time

 Brad, I think this approach should work at other GPC sites. I'd appreciate
 if you'd (have George) take a look.

--
Ticket URL: 
<http://informatics.gpcnetwork.org/trac/Project/ticket/551#comment:8<https://urldefense.proofpoint.com/v2/url?u=http-3A__informatics.gpcnetwork.org_trac_Project_ticket_551-23comment-3A8&d=CwMFaQ&c=yHlS04HhBraes5BQ9ueu5zKhE7rtNXt_d012z2PA6ws&r=CqPxCu-EywA2wo4iO-6BFqfwPQ2roHdsnjQi7SSLgLE&m=yqG12qsoyrBif-jILwubW8btm4qM0DM258CMGa2kQBI&s=3Jny2FAhAcvq_hCSSoufzQEnkPPqO44JMAU_Zi_XbQs&e=>>

gpc-informatics 
<http://informatics.gpcnetwork.org/<https://urldefense.proofpoint.com/v2/url?u=http-3A__informatics.gpcnetwork.org_&d=CwMFaQ&c=yHlS04HhBraes5BQ9ueu5zKhE7rtNXt_d012z2PA6ws&r=CqPxCu-EywA2wo4iO-6BFqfwPQ2roHdsnjQi7SSLgLE&m=yqG12qsoyrBif-jILwubW8btm4qM0DM258CMGa2kQBI&s=b8Ln6oogSoCgdKEAkaGuJNxyO_HhjpaET5QTlwV-1gE&e=>>
Greater Plains Network - Informatics



--

Al’ona Furmanchuk, Ph.D.
Research Associate

Center for Health Information Partnerships,
Northwestern University, Feinberg School of Medicine

633 N. Saint Clair Street, 20th floor,
Chicago, IL 60611

Web: 
http://furmanchuk.com/<https://urldefense.proofpoint.com/v2/url?u=http-3A__furmanchuk.com_&d=CwMFaQ&c=yHlS04HhBraes5BQ9ueu5zKhE7rtNXt_d012z2PA6ws&r=CqPxCu-EywA2wo4iO-6BFqfwPQ2roHdsnjQi7SSLgLE&m=yqG12qsoyrBif-jILwubW8btm4qM0DM258CMGa2kQBI&s=VNFtxnmsnEgN7YNkkxnbm6_yI2aPx3BrxZLIEe8cUYc&e=>
E-mail: alona.furmanc...@northwestern.edu<mailto:furmanc...@icnanotox.org>

Phone: 312-503-34281



________________________________

UT Southwestern


Medical Center



The future of medicine, today.




--

Al’ona Furmanchuk, Ph.D.
Research Associate

Center for Health Information Partnerships,
Northwestern University, Feinberg School of Medicine

633 N. Saint Clair Street, 20th floor,
Chicago, IL 60611

Web: 
http://furmanchuk.com/<https://urldefense.proofpoint.com/v2/url?u=http-3A__furmanchuk.com_&d=CwMFaQ&c=yHlS04HhBraes5BQ9ueu5zKhE7rtNXt_d012z2PA6ws&r=CqPxCu-EywA2wo4iO-6BFqfwPQ2roHdsnjQi7SSLgLE&m=yqG12qsoyrBif-jILwubW8btm4qM0DM258CMGa2kQBI&s=VNFtxnmsnEgN7YNkkxnbm6_yI2aPx3BrxZLIEe8cUYc&e=>
E-mail: alona.furmanc...@northwestern.edu<mailto:furmanc...@icnanotox.org>

Phone: 312-503-34281

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Al’ona Furmanchuk, Ph.D.
Research Associate

Center for Health Information Partnerships,
Northwestern University, Feinberg School of Medicine
633 N. Saint Clair Street, 20th floor,
Chicago, IL 60611
Web: http://furmanchuk.com/
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