Dr. Bernie Black and Alona Furmanchuk from Northwestern University would like to discuss a COVID-related research project and GPC data request that they are preparing. Following is a short description of the project.
Background: The COVID-19 pandemic has led to a sharp drop in non-COVID-19 patients seeking emergency department (ED) care, including care for heart attack, stroke, and other life-threatening conditions. ED-avoidance may be contributing to a rise in population mortality, beyond deaths attributable to COVID-19. Broad idea: Provide rapid evidence from sites in high and low COVID-19 incidence areas on the extent of: (i) overall ED avoidance; (ii) avoidance for major cardiovascular conditions (AMI, heart failure, stroke). Divide AMI into STEMI and nSTEMI. Divide stroke into ischemic and hemorrhagic. Assess any differences by geographic area (high versus low COVID-19 risk) gender, age (over versus under 65), and major racial/ethnic groups. Assess selected outcomes that may be associated with delayed arrival. The research design will be interrupted time series ITS), using the same time period in 2019 to control for seasonality. We plan to seek rapid publication, which can then form the basis for a grant application, likely to a private foundation (e.g., Robert Wood Johnson; Commonwealth), which will allow us to continue and expand this research over time as the COVID-19 pandemic evolves. To support rapid turnaround, we will provide to each site detailed instructions on Tables and other analytical results to be returned, and SAS and SQL code, designed to be applied to PCORnet common data model data, which can be adapted as needed. We will distribute queries during the week of June 8, and ask for replies as fast as possible. Challenge: Need to move fast and stay ahead of the research curve. COVID-19 research knowledge is moving extremely rapidly. ED avoidance without more is now widely known and well-documented. Studies exist reporting sharp declines in AMI, stroke, and heart failure ED visits, but our preliminary data shows much smaller changes for AMI and stroke, and important differences between STEMI and nSTEMI, and between ischemic and nonischemic stroke. No published or preprint studies have yet looked closely at outcomes, to assess the evidence for delayed arrivals, nor at disparities and cross-sectional variation. Thank you! Mei From: Gpc-dev <[email protected]> On Behalf Of Dan Connolly Sent: Monday, June 08, 2020 9:32 AM To: [email protected] Subject: gpc-dev 9 Jun agenda and meeting notes What else for tomorrow? I found just a few things but they seem worth a short meeting. Intermountain is scheduled to scribe https://docs.google.com/document/d/1LjxSYeJFeeAhdwNrzXAoACslKS6spEG_jItGScmt1fU/edit agenda snapshot: 1. Convene, take roll, review records and plan the next meeting(s). * 11:00 a.m. Central Time. Meeting ID and access code: 817-393-381<https://global.gotomeeting.com/meeting/join/817393381>; call +1 (571) 317-3131 * Roll; Reminder - put site after your name in GoToMeeting<https://global.gotomeeting.com/meeting/join/817393381> preferences GPC DevTeams<https://informatics.gpcnetwork.org/trac/Project/wiki/DevTeams> represented? KUMC (chair), UIOWA, MCW, MCRI, UNMC, UTHSCSA, UTSW, MU, IndianaU, Utah, Allina, Intermountain (scribe), UTH * Comments on the agenda? (ref SoftwareDev#tracking<https://informatics.gpcnetwork.org/trac/Project/wiki/SoftwareDev#tracking>) On last week’s notes?<https://docs.google.com/document/d/1LjxSYeJFeeAhdwNrzXAoACslKS6spEG_jItGScmt1fU/edit#heading=h.9ioc8gnd1ijp> (#12<https://informatics.gpcnetwork.org/trac/Project/ticket/12>) Recent tickets opened/closed<https://informatics.gpcnetwork.org/trac/Project/timeline> - FYI (i.e. not intended for discussion) * None this week * Next meeting(s): Jun 16; scribe: Marshfield? MCW? * Note scribe rotation<https://docs.google.com/document/d/1fPoDn0pdVvC-Mct58X7wkGD2rNiId8aNZ9JG_WCbcf4/edit#heading=h.zbjzupqx0rh7> appendix 1. Milestone:tumor-reg-18<https://informatics.gpcnetwork.org/trac/Project/milestone/tumor-reg-18> * #760 (duplicates in tumor table: collect data from sites) <https://informatics.gpcnetwork.org/trac/Project/ticket/760>#749<https://informatics.gpcnetwork.org/trac/Project/ticket/749> PCORNet style TUMOR table<https://informatics.gpcnetwork.org/trac/Project/ticket/749> * Cancer CRG is requesting real dates to conduct quality control work; Brad/Brian has the ball - UIOWA will present on the Gov call tomorrow (6/3) * UIOWA used R code to create the NAACCR table. Done: R script for NAACCR to PCORnet tumor table <http://listserv.kumc.edu/pipermail/gpc-dev/2020q2/010993.html> Gryzlak, Brian M * DC to ... prepare demonstration for gpc-dev - slipped another 2 weeks 1. milestone:covid19wk<https://informatics.gpcnetwork.org/trac/Project/milestone/covid19wk> * #759<https://informatics.gpcnetwork.org/trac/Project/ticket/759> covid19 PCORNet datamarts<https://informatics.gpcnetwork.org/trac/Project/ticket/759> * PCORnet 2.0 Steering Committee Meeting 5/26: … pause additional ETL development until PCORI completes its review… Russ may get more info Jun 2 1. #411<https://informatics.gpcnetwork.org/trac/Project/ticket/411> Jim C - offered to share RxNorm metadata from last i2b2 build with KUMC - done. wash your hands ...<https://www.cdc.gov/coronavirus/2019-ncov/prepare/prevention.html> -- Dan
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