On 6/8/14, 3:38 AM, Albert wrote:
Hello:

I am using g_lie to evaluate my ligand binding affinity with command:

g_lie_mpi -f ener.edr -e 10000 -ligand POC


but I get following results:


Opened ener.edr as single precision energy file
Using the following energy terms:
LJ:
Coul:

Back Off! I just backed up lie.xvg to ./#lie.xvg.2#
Last energy frame read 8114 time 10253.000
DGbind = 0.000 (0.000)

gcq#165: "Welcome to the Power Age" (2 Unlimited)


I am just wondering what's happennig?


Probably a combination of things, including not saving the right energy groups and missing several important command-line options.

-Justin

--
==================================================

Justin A. Lemkul, Ph.D.
Ruth L. Kirschstein NRSA Postdoctoral Fellow

Department of Pharmaceutical Sciences
School of Pharmacy
Health Sciences Facility II, Room 601
University of Maryland, Baltimore
20 Penn St.
Baltimore, MD 21201

[email protected] | (410) 706-7441
http://mackerell.umaryland.edu/~jalemkul

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