There are a few review article where the strategy and guidelines are described. 
You can find this material on the cgmartini.nl website. 

> On Aug 29, 2014, at 2:03, Sridhar Kumar Kannam <srisri...@gmail.com> wrote:
> 
> Dear Gromacs users,
> 
> I have very recently started working with  Gromacs and Martini force field.
> I am able to generate the coarse-grained model for HIV Protease (1hvr.pdb).
> I want to simulate the protein along with its inhibitor. Are there any
> guidelines for building (coarse-graining) its inhibitor ?
> 
> Sorry for the naive question ...
> 
> Thank you.
> 
> 
> 
> 
> 
> 
> -- 
> Cheers !!!
> Sridhar  Kumar Kannam :)
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