Here is a starting point to install GTK on OSX:
http://live.gnome.org/GTK%2B/OSX/
And It can running separately from X in OSX?
Not yet.
Actually you can run it separately from X server, like an ordinary
application, when using Quartz backend.
What you need is is to check GTK-OSX project, see more info here:
http://www.gtk.org/download/macos.php
Basically, you need to build GTK with jhbuild scripts and bundle the GTK
libraries with your program.
Regards,
Miroslav
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