urgh - yes you're right.


> On 16 Feb 2015, at 16:47, Glasser, Matthew <glass...@wusm.wustl.edu> wrote:
> 
> Also to Steve: if these are used after ICA+FIX, don’t they need to have the 
> 24 motion parameters and noise ICA component timeseries confounds regressed 
> out as well, before being used on the cleaned data?
> 
> Peace,
> 
> Matt.
> 
> From: <Harms>, Michael <mha...@wustl.edu <mailto:mha...@wustl.edu>>
> Date: Monday, February 16, 2015 at 10:42 AM
> To: Matt Glasser <glass...@wusm.wustl.edu <mailto:glass...@wusm.wustl.edu>>, 
> Stephen Smith <st...@fmrib.ox.ac.uk <mailto:st...@fmrib.ox.ac.uk>>, Miriam 
> Klein-Flügge <miriam.klein-flu...@psy.ox.ac.uk 
> <mailto:miriam.klein-flu...@psy.ox.ac.uk>>
> Cc: "hcp-users@humanconnectome.org <mailto:hcp-users@humanconnectome.org>" 
> <hcp-users@humanconnectome.org <mailto:hcp-users@humanconnectome.org>>
> Subject: Re: [HCP-Users] Incorporating physiological monitoring data
> 
> 
> Not only that, but just because a given physiological trace exists, doesn't 
> necessarily mean that it is a *good* trace.  There is going to be 
> considerable variability in the quality of the physiological measurements, 
> which presents a challenge in using them in a large scale study.  I'm sure 
> that Greg will comment more when he has a chance.
> 
> cheers,
> -MH
> 
> -- 
> Michael Harms, Ph.D.
> -----------------------------------------------------------
> Conte Center for the Neuroscience of Mental Disorders
> Washington University School of Medicine
> Department of Psychiatry, Box 8134
> 660 South Euclid Ave.  Tel: 314-747-6173
> St. Louis, MO  63110  Email: mha...@wustl.edu <mailto:mha...@wustl.edu>
> 
> From: <Glasser>, Matt Glasser <glass...@wusm.wustl.edu 
> <mailto:glass...@wusm.wustl.edu>>
> Date: Monday, February 16, 2015 10:10 AM
> To: Stephen Smith <st...@fmrib.ox.ac.uk <mailto:st...@fmrib.ox.ac.uk>>, 
> Miriam Klein-Flügge <miriam.klein-flu...@psy.ox.ac.uk 
> <mailto:miriam.klein-flu...@psy.ox.ac.uk>>
> Cc: "hcp-users@humanconnectome.org <mailto:hcp-users@humanconnectome.org>" 
> <hcp-users@humanconnectome.org <mailto:hcp-users@humanconnectome.org>>
> Subject: Re: [HCP-Users] Incorporating physiological monitoring data
> 
> Note that a major reason we didn’t use these physiological confound 
> regressors was they don’t exist for every subject, so be sure to select a 
> subset of subjects that have them.  We’d also be interested to know if you 
> found they were helpful.
> 
> Peace,
> 
> Matt.
> 
> From: Stephen Smith <st...@fmrib.ox.ac.uk <mailto:st...@fmrib.ox.ac.uk>>
> Date: Monday, February 16, 2015 at 8:05 AM
> To: Miriam Klein-Flügge <miriam.klein-flu...@psy.ox.ac.uk 
> <mailto:miriam.klein-flu...@psy.ox.ac.uk>>
> Cc: "hcp-users@humanconnectome.org <mailto:hcp-users@humanconnectome.org>" 
> <hcp-users@humanconnectome.org <mailto:hcp-users@humanconnectome.org>>
> Subject: Re: [HCP-Users] Incorporating physiological monitoring data
> 
> Hi - I think you would probably be best off taking the FIX-cleaned version of 
> the data, and then apply additional confound regressors if they will help.  
> Don't forget to apply the same highpass filter (to those regressors) that was 
> applied already in the data preproc, before you use them.
> 
> Cheers.
> 
> 
> 
>> On 16 Feb 2015, at 13:35, Miriam Klein-Flügge 
>> <miriam.klein-flu...@psy.ox.ac.uk <mailto:miriam.klein-flu...@psy.ox.ac.uk>> 
>> wrote:
>> 
>> Dear all,
>> Is it correct that until now the physiological monitoring data is not made 
>> use of in the preprocessing of the rfMRI data? I would like to correct for 
>> cardiac and respiratory signals and wondered how to best do that. I can see 
>> that FIX-denoising probably takes care of this type of noise but I am 
>> particularly interested in looking at the brain stem and in my experience, 
>> including physiological regressors in the preprocessing makes a big 
>> difference there.
>> Would you recommend using the spatially (minimally) pre-processed rfMRI 
>> data, performing the high-pass filtering on it myself and then incorporating 
>> the physiological regressors at that stage, or is there a better stage at 
>> which to do it? Also, is there a standard procedure for regressing out the 
>> physiological regressors that you can recommend?
>> Many thanks in advance!
>> Kind regards,
>> Miriam
>> -- 
>> Miriam Klein-Flügge
>> Sir Henry Wellcome Postdoctoral Fellow
>> Department of Experimental Psychology
>> University of Oxford
>> 
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> 
> ---------------------------------------------------------------------------
> Stephen M. Smith, Professor of Biomedical Engineering
> Associate Director,  Oxford University FMRIB Centre
> 
> FMRIB, JR Hospital, Headington, Oxford  OX3 9DU, UK
> +44 (0) 1865 222726  (fax 222717)
> st...@fmrib.ox.ac.uk <mailto:st...@fmrib.ox.ac.uk>    
> http://www.fmrib.ox.ac.uk/~steve <http://www.fmrib.ox.ac.uk/~steve>
> ---------------------------------------------------------------------------
> 
> Stop the cultural destruction of Tibet <http://smithinks.net/>
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Associate Director,  Oxford University FMRIB Centre

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