Re: [HCP-Users] Probabilistic structural dense connectome

[Glasser, Matthew]

It’s coming.  We’ve (mostly the Oxford diffusion group) put a large amount of effort into getting the neurobiologically most reasonable tractography results we can from our data and that has taken time.  We're sorry for the delay, but usually the HCP has taken the approach to only release stuff once the major stakeholders have come to a scientific consensus on it.  In so far as we’ve waited to release things until we get scientific consensus, we’ve released more accurate, more forward looking data and software products that will be better in the long run for our users.  There always is a tension between releasing something sooner that isn’t as good, vs releasing something better later, but the minimally processed diffusion data are available to any investigators wishing to start analyzing it now.   Peace, Matt. From: Michael Dwyer <mgdw...@bnac.net> Date: Friday, March 13, 2015 at 12:56 PM To: "hcp-users@humanconnectome.org" <hcp-users@humanconnectome.org> Subject: [HCP-Users] Probabilistic structural dense connectome Dear HCP experts, I would like to do some analysis in subjects with substantial lesion loads (multiple sclerosis) where tractography may be difficult or unreliable. I am wondering whether the HCP project contains a dense group-probabilistic connectome for structural (diffusion) connectivity. Basically, I would like to be able to normalize my subjects to an atlas using hi-res T1 images (and potentially also DTI using something like ANTs multi-cost-function warping). I would then like to have the ability to query each white matter voxel in normalized space to get a probabilistic connectivity map. I realize such a dense connectome map would be enormous, but I know you guys are dealing with huge data in your sleep nowadays, so I though maybe something like this might be available. Thanks in advance! All the best, Mike -- Michael G. Dwyer, Ph.D. Assistant Professor of Neurology and Biomedical Informatics Director of Technical Imaging Development Buffalo Neuroimaging Analysis Center University at Buffalo 100 High St. Buffalo NY 14203 mgdw...@bnac.net (716) 859-7065 _______________________________________________ HCP-Users mailing list HCP-Users@humanconnectome.org http://lists.humanconnectome.org/mailman/listinfo/hcp-users   The materials in this message are private and may contain Protected Healthcare Information or other information of a sensitive nature. If you are not the intended recipient, be advised that any unauthorized use, disclosure, copying or the taking of any action in reliance on the contents of this information is strictly prohibited. If you have received this email in error, please immediately notify the sender via telephone or return mail. _______________________________________________ HCP-Users mailing list HCP-Users@humanconnectome.org http://lists.humanconnectome.org/mailman/listinfo/hcp-users