Usually in the deep white matter, but not in the cortex.  I would recommend 
using TBSS for comparing white matter across subjects.  In the future we will 
hopefully be able to offer data aligned based on fiber orientations.

Peace,

Matt.

From: 
<hcp-users-boun...@humanconnectome.org<mailto:hcp-users-boun...@humanconnectome.org>>
 on behalf of Aaron C <aaroncr...@outlook.com<mailto:aaroncr...@outlook.com>>
Date: Thursday, December 21, 2017 at 3:12 AM
To: "hcp-users@humanconnectome.org<mailto:hcp-users@humanconnectome.org>" 
<hcp-users@humanconnectome.org<mailto:hcp-users@humanconnectome.org>>
Subject: [HCP-Users] A question about registering the HCP diffusion data to the 
standard space


Dear HCP experts,


I have a question about registering the HCP diffusion data to the standard 
space for cross-subject analysis. I see the file "acpc_dc2standard.nii.gz" in 
the folder ${StudyFolder}/${Subject}/MNINonLinear/xfms/


Would you please suggest if the following command would be appropriate:


applywarp --ref=MNI152_T1_1mm --in=dti_FA.nii.gz --warp=acpc_dc2standard.nii.gz 
--out=dti_FA_warped.nii.gz


Should I use any reference image specific for the HCP data instead of 
"MNI152_T1_1mm"? After this registration step, I guess the white matter voxels 
in the file "dti_FA_warped.nii.gz" should be comparable across different 
subjects? Thank you.

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