Hi Damian, I suffered a similar problem which I reported to the forum:
http://hdf-forum.184993.n3.nabble.com/Deploying-HDF5DotNet-causes-Could-not-load-file-td402678 3.html My issue was missing C++ runtime DLLs: Msvcp100.dll Msvcr100.dll I got these from the 'Binaries' mentioned at http://hdf5.net/ I included these two DLLs in the runtime path of my app. so that the HDF5DotNet wrapper can find them. I guess you would want them in the target path for your deployments as well. Graeme
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