Pierre Neidhardt <ambre...@gmail.com> writes:

> Guix already supports cross-compilation out of the box of 32-bit
> packages on any architecture:
>
>       guix build --system=i686-linux PACKAGES...
>
> Now the question is: is it possible to run the produced binaries
> directly (no VM)?

Yes, you can run i686 binaries directly on a x86_64 system with the default 
libre
linux kernel (which have i686 support enabled), one example is the
‘wine’ package.

>
> Many other distributions have support for the so-called "multilibs",
> that is, a separate 32-bit library tree with the 32-bit linker
> configured to load those instead of their 64-bit counterparts.
>
> Does Guix have any provision for multilibs?

Guix install every package into its own directory which already cover
the multilibs cases.

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