I was just doing some research on the original question posted of gloves suitable for handling xylene. Nitrile is a synthetic rubber made of acrylnitrile and butadiene, devoid of allergy-causing proteins like in latex and natural rubber.

The U.S. Dept. of Energy suggests using nitrile when handling xylenes, Ansell suggests either their laminate film gloves, PVA, or nitrile on their very detailed chart offering technical permeabilty data (for instance, it takes 75 min for xylene to break through their nitrile gloves). Now according to OSHA, nitrile does not provide adequate protection, but gives other glove types that are in agreement with what is suggested by some of the other sites I saw. Some of the sites don't seem to say how THICK these gloves are that they are rating, which I think would be a factor for permeability rate. Most of Ansell's gloves were quite THICK (like for industrial use).

Another factor for permeability would be how long xylene will be in contact with your glove, if you change gloves frequently or soon after getting xylene on them it seems you'd be ok. I find nitrile (the flexible thin healthcare ones) to be pretty cost-effective. At least, I've dipped my nitrile-gloved fingers in a xylene bath and when I changed my gloves a few minutes later my skin and the inside of the glove was still dry.

References:
http://www.aps.anl.gov/Safety_and_Training/User_Safety/gloveselection.html

http://www.ansellpro.com/download/Ansell_7thEditionChemicalResistanceGuide.pdf

http://www.osha.gov/SLTC/healthguidelines/xylene/recognition.html


Regards,
Merced

--On Wednesday, September 02, 2009 1:53 PM -0400 "Bonner, Janet" <janet.bon...@flhosp.org> wrote:

It says on the box that these aloe touch nitrile gloves are "Latex-free,
powder-free nitrile examination gloves, single use, non-sterile. Tested
for use with chemotherapy drugs"     We've had a terrible time with
getting good gloves, and then when we get some good ones, they are
replaced the following year with a cheaper brand until our PAs start
screaming.  You're right - Surgery wouldn't even have to whistle!!
Janet

________________________________

From: histonet-boun...@lists.utsouthwestern.edu on behalf of Robert
Richmond Sent: Wed 9/2/2009 1:34 PM
To: histonet@lists.utsouthwestern.edu
Subject: [Histonet] Re: Gloves



Janet Bonner notes:

We use Aloe Touch Nitrile gloves, powder-free from Medline (MDS195084
for small size)  www.medline.com.        (1-800 - medline) These gloves
are not stiff, they fit the hand 'like a glove' .  They say on the box
"not intended to be used as a chemical barrier", but they do a great job
when exposed to Histology chemicals.<<

Not familiar with this product, but with nitrile rubber gloves brand
name is important, as the quality of nitrile rubber gloves worsens.
When they first came out and were made in the USA, I could make a pair
last for two weeks of grossing. As manufacture moved to the
latex-producing countries, nitrile rubber (if that's what they
actually are) gloves became no better than latex. At present I use two
pairs of gloves when I gross.

There's a little-known product called "chemotherapy gloves" - thick
blue latex. I filched a box of these and use them - they last for
several days. Obviously re-using gloves offsets the high initial cost
of purchase, but that's not good MBA thinking.

OSHA says not to handle formaldehyde (and I suppose xylene) with latex
gloves, but has not specified an alternative.

It's disgraceful how little the powers that be care about the hands of
pathologists and histotechnologists. You can bet that if it were
nurses who had this problem, it'd get solved in a hurry.

Bob Richmond
Samurai Pathologist
Knoxville TN

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Merced M Leiker
Research Technician II
Cardiovascular Medicine
348 Biomedical Research Building
State University of New York at Buffalo
3435 Main St, Buffalo, NY 14214  USA
lei...@buffalo.edu
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716-829-2665 (Fx)

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