We have always noticed, at least in the middle/inner ear, that newly deposited bone stains darker than mature bone, both with H&E and toluidine blue. Is this increased eosinophilic quality due to a lack of mineralization and therefore higher density of osteoid components in the new bone or some other difference in composition of the osteoid? The contrast is quite striking when we observe bone remodeling due to middle ear infections, so I wanted to be able to offer an accurate explanation of why that is...
Patricia Keller Sr. Research Tech/Core Histologist Washington University School of Medicine Department of Otolaryngology 4566 Scott Ave Campus Box 8115 St. Louis, Mo 63110 314-747-7166 This email and any files transmitted with it are confidential and intended solely for the use of the individual or entity to whom they are addressed. If you have received this email in error please notify the system manager. This message contains confidential information and is intended only for the individual named. If you are not the named addressee you should not disseminate, distribute or copy this e-mail. _______________________________________________ Histonet mailing list Histonet@lists.utsouthwestern.edu http://lists.utsouthwestern.edu/mailman/listinfo/histonet
