Don't know if you can get one, but far and away,  my favorite microtome of all 
time is the Microm HM-325 (not the newer HM325-2's).   Block orientation can be 
accomplished one handed because of the positioning of the orientation screws (X 
orientation at left, and Y atop the chuck).  The plate on the knife holder and 
base upon which rests the blade carrier assembly is black in color.  Doesn't 
sound like much, but this helps tremendously in visually aligning the block 
face to the knife when you have to recut blocks.  And these are the easiest 
microtomes in the world to adjust.  I was a supervisor at a reference lab with 
14 of these microtomes.  I've "repaired" these when someone has overtightened 
levers on far too many occasions to count and it is a snap to do so.  All you 
need is a set of allen wrenches and a screwdriver or two. 

Good luck!    

Brian D. Cooper, HT (ASCP)CM | Histology Supervisor 
Department of Pathology and Laboratory Medicine
Children's Hospital Los Angeles 

-----Original Message-----
From: histonet-boun...@lists.utsouthwestern.edu 
[mailto:histonet-boun...@lists.utsouthwestern.edu] On Behalf Of Sylvia Shockey
Sent: Monday, June 02, 2014 2:20 PM
To: histonet@lists.utsouthwestern.edu
Subject: [Histonet] Microtome


Hello,
                   My name is Sylvia Shockey I work in a histology lab. One of 
our microtomes is not working properly and would appreciate some advice on 
purchasing a new one or maybe refurbished.  I have had some quotes on a Tanner 
scientific manual rotary microtome, titan 5000 . Thermo Shandon Finesse and a 
Thermo Shandon Microm HM325. Mr. Grimm with Thermo fisher has new and used on 
both of these models. Help me please I don't want to buy a clunker.  Thanks for 
your time.





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