We are in the process of bringing this on-line. We are using a rabbit monoclonal (clone D5F3) from Cell Signaling Technologies (Danvers, MA). There are cases that are obviously positive and then there cases that are "Equivocal" (like HER2) where you need to do the FISH test. The advantages of the IHC are less cost, faster result, can be used on specimens with limited tumor cells present, and it may prove useful for those tumors that show genomic heterogeneity.
Richard Richard W. Cartun, MS, PhD Director, Histology & Immunopathology Director, Biospecimen Collection Programs Assistant Director, Anatomic Pathology Hartford Hospital 80 Seymour Street Hartford, CT 06102 (860) 972-1596 (860) 545-2204 Fax -----Original Message----- From: [email protected] [mailto:[email protected]] On Behalf Of Mark Tarango Sent: Thursday, October 23, 2014 4:41 PM To: [email protected] Subject: [Histonet] ALK IHC Does anyone stain lung cancer specimens for ALK using IHC? If not, any opinions? thanks Mark _______________________________________________ Histonet mailing list [email protected] http://lists.utsouthwestern.edu/mailman/listinfo/histonet This e-mail message, including any attachments, is for the sole use of the intended recipient(s) and may contain confidential and privileged information. Any unauthorized review, use, disclosure, or distribution is prohibited. If you are not the intended recipient, or an employee or agent responsible for delivering the message to the intended recipient, please contact the sender by reply e-mail and destroy all copies of the original message, including any attachments.
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