Hi Mary Ann,

It seems that you’re having a problem with either your block assembly or your 
blade holder assembly.  I would have your microtome serviced, it may be the 
block clamp isn’t tight enough or you have knicks on your blade holder.  If 
you’re block clamp is ok, I would lean more on the blade holder needing to be 
repaired or replaced. The older blade holder assemblies cost more, as they were 
fabricated to last longer before giving issues with microtomy.  The newer 
microtome assemblies can easily knick and give thick and thin sections, and in 
this case giving 1 good section, followed by a section that is chunking out.

Hope this helps!

Cheers,
Eddie Martin, HTL, HT(ASCP), QIHC(ASCP)
Histology Technical Supervisor
The National Institutes of Health
The Clinic Center
Department of Laboratory Medicine
10 Clinic Dr
Bethesda, MD 20814

> On Jul 8, 2018, at 1:00 PM, histonet-requ...@lists.utsouthwestern.edu wrote:
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>   1. Prostate biopsy (Mary Ann)
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> From: Mary Ann <yes...@comcast.net>
> Subject: [Histonet] Prostate biopsy
> Date: July 7, 2018 at 2:29:13 PM EDT
> To: histonet@lists.utsouthwestern.edu
> 
> 
> I have an issue with our prostate needle biopsy chipping out of the block on 
> sectioning.
> One block out of 12 will demonstrate this phenomenon.  The block will section 
> well then a section with chip right out.
> 
> Sent from my iPhone
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