Hi Carole, Sorry but you need to validate the change completely. Reagent alcohols are blends that sometimes don’t even contain ethanol. You need to demonstrate that it doesn’t affect routine H&Es, special stains, and IHC. Plus you have to test the major tissue types you routinely work on.
Others may disagree with me, but if you get an inspector who focuses on the minutia, you can get cited. Paula Sent from my iPhone > On Feb 6, 2020, at 12:13 PM, Johnson, Carole via Histonet > <histonet@lists.utsouthwestern.edu> wrote: > > We have been using ethanol in our lab and would like to change to using > reagent alcohol for the obvious reasons of cost and regulatory headaches. I > have been tasked with creating a validation/verification process. Does > anyone have any suggestions? Or better yet, information proving that we can > make the change without going through an extensive project? Thanks! > > Carole L Johnson, HT(ASCP)cm, QIHC(ASCP)cm > Histotechnologist > UCH/Memorial Central Hospital > Histology Laboratory > 1400 Boulder Street > Colorado Springs, CO > O 719.365.5204 > carole.john...@uchealth.org<mailto:carole.john...@uchealth.org> > > CONFIDENTIALITY NOTICE: This message and any attachments may contain > privileged and confidential peer review, risk management, and/or quality > management information pursuant to the Colorado Professional Review Act, > C.R.S. 12-36.5-101, et seq., the Colorado Hospital Licensing law, C.R.S. > 25-3-109, the Quality Management Programs law, C.R.S. 25-35-904, and other > corresponding provisions of federal and state law. Please maintain the > strict confidentiality of this information. If you are not the intended > recipient, you are notified that any disclosure, copying, distribution, > electronic storage or use of this communication is prohibited. If you > received this communication in error, please notify us immediately by e-mail, > attaching the original message, and delete the original message from your > computer and any network to which your computer is connected. > > > > _______________________________________________ > Histonet mailing list > Histonet@lists.utsouthwestern.edu > http://lists.utsouthwestern.edu/mailman/listinfo/histonet _______________________________________________ Histonet mailing list Histonet@lists.utsouthwestern.edu http://lists.utsouthwestern.edu/mailman/listinfo/histonet
