I'm heading for Merak myself.  $460 for unlimited domains/users, or
for $960 the pro version with the high-speed memory mode.  I've heard
good reviews on the product, that say it can handle whatever you throw
at it but its a bit daunting to configure unless you know mail
servers.  Don't know how true any of that is, but I'll find out.

I feel for Scott.  This has to be a crushing blow to Declude (and its
new owners), which has yet to come out with a version for any other
mail server.  I hope they can hang on long enough to diversify.

As for a/v and antispam, I moved to the free and open source ASSP
quite some time ago, and once you get it trained (which was
surprisingly easy even with my general-ISP client base) its totally
maintenance-free and highly effective with essentially zero
false-positives.

Its primarily a Bayesian filter, but it also has SPF, supports
user-defined white- and blacklists, includes antivirus (I still use
Declude Junkmail but I guess that has to change) and has just
introduced a rudimentary RBL feature.  Me personally I have never
needed more than the Bayes filter and the HELO check that also is in
there.

-- 
--Matt Robertson--
President, Janitor
MSB Designs, Inc.
mysecretbase.com

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