The mice-software (S+) is quite felxible:
http://web.inter.nl.net/users/S.van.Buuren/mi/hmtl/mice.htm
PM
SR Millis wrote:
>
> As a novice to multiple imputation methods, I'm looking for advice
> regarding appropriate approaches to handling missing data in the
> following situation:
>
> I have 3 groups of patients with different brain lesion patterns. The
> patients have been given a battery of 6 cognitive tests assessing
> memory, reasoning, visuoperceptual functioning, etc. But not all
> patients were able to complete all 6 cognitive tests. There are
> supplemental data, eg, age, education, etc.
>
> I want to examine group differences on the cognitive tests. In the past,
> with complete case analysis, I have used ANOVA, MANOVA, or logistic
> regression. With this data set, I would like to use multiple imputation
> to handle the missing congitive test data. In the past, I have used SAS
> proc MI, SOLAS, or F Harrel's splus transcan program for multiple
> imputation.
>
> In this 3 group case, I would appreciate any advice regarding imputation
> and modeling strategies. For example, in SOLAS I am unable to combine
> ANOVA results from the individual imputed data set analyses.
>
> Thanks,
> SR Millis
--
P. Malewski | Carl-Neuberg-Str. 1
Hannover Medical School | Tel.:+49 511 532 3194
Dep. of Psychosomatics and Psychotherapy | Fax.:+49 511 532 3190
