US Stock-Market - Stock Profile of the Week

Symbol: HTDS
Market: PK
Sector: MEDICAL RESEARCH

The Last time HTDS was at this price level it went from .038 to 10 cents i= n just a few days.


Before we begin our profile we have very exciting, breaking news...

Tubercin Passes Toxicity Trials - Ready To Proceed To Live Cancer Trials

BREAKING NEWS - DELRAY BEACH, Fla.--(BUSINESS WIRE)--Hard to Treat Disease= s Incorporated (Pink Sheets:HTDS) announces that Tubercin=AE has passed the = toxicity tests required to proceed to the live cancer trials. Testing Tubercin=AE o= n live Melanoma, Lung and Breast cancer cells will begin immediately. The Preside= nt and CEO, Mr. Colm J. King, met with the spokesperson of the medical team at th= eir offices in Oklahoma City. Mr. King was advised that the tests were conduct= ed under strict FDA (Federal Drug Administration) guidelines. Full test resul= ts will be available at the corporate offices as soon as the reports and find= ings are printed.

"These are the most promising results to date regarding Tubercin=AE a= nd we're looking forward to additional positive results in the near future," s= tated Mr. King. "These tests prove that Tubercin=AE is non-toxic and is the fir= st step on the way to human clinical trials as well as the first positive break-throu= gh conducted in the United States with an independent medical team for Tuberc= in=AE."

Operating out of Delray Beach, Florida, Hard to Treat Diseases Incorporate= d ("HTTD") holds the international marketing rights, except South Korea, to Tubercin=AE= , a patented immunostimulant developed for combating Cancer under medical pate= nt (US Patent 6,274,356). The unique properties unlike other cancer products are = clearly stated in the abstract summary of the patent... "A carbohydra= te complex, which is a mixture of low molecular-weight polysaccharides of an arabinoma= nnan structure extracted from Mycobacterium tuberculosis, is highly effective i= n treating various cancer patients without incurring any adverse side effect= s."



STOCK PROFILE OF THE WEEK

HTDS is now at an emerging and potentially explosive stage. As stated in t= heir press release, Tubercin is now ready to proceed (after tests conducted und= er strict FDA guidelines) to human clinical trials. While they have jumped on= e very big hurdle, they are still in the early stages of development and now is a= great time for investors to take heed.



TUBERCIN

Over the past ten years, epoch making anticancer agents have continuously = been introduced, but the mortality of cancer patients have been rising in the U= S. and the European countries not to mention Japan and Korea. The decisive me= asure to cope with cancer is surgery.


When the cancer cells spread throughout a person instead of remaining on t= he original spot, the treatment should take into consideration chemotherapy, = radiation therapy and immunotherapy. The drawback of such therapies, howev= er, is they incur damages not only on cancer cells, but also on the normal cells.=


Chemotherapy and radiation therapy are not suitable for application on wea= kened patients, especially those above 70. Historically, various forms of immunotherapy have been performed, falling short of therapeutic expectatio= n. When Bacille calmetteguerin is used as an active no-specific immunotherape= utic agent, however, the patient's prognosis turns better through a simulative = action on immune system of the cancer case.


Professor T.H. Chung of Korea extracted carbohydrate complex Tubercin from= microbacterium tuberculosis to be used as immunostimulant. This was meant = to activate the T-lymphocyte of the cancer patient to produce lymphokine. Thi= s process strengthened and promoted immuno surveillance activities in defici= ent state and alleviated the pain and prolonged the life of cancer patients.

Of late the pharmaceutical industry in advanced countries started to put o= n the market so called cancer vaccines (active specific immunotherapy). The vacc= ines, bacterial extracts, as adjuvants, with autologous and or allogenic cancer = cells to generate antibodies to cancer cells, facilitating the killer T-cells to= recognize and destroy cancer cells.


The laboratory work to modify autologous or allogenic cancer cells are not= ordinary and simple. When our lab work augments the active specific immunotherapeutic agents, the Tubercin will be one of the best adjuvants. = Meanwhile, the main point of AIDS is its virus killing T-cells and Tuberci= n helps maintain healthy T-cells. Consequently, we focus our effort on the application of Tubercin to AIDS.


TUBERCIN is derived from micro bacterium tuberculosis. As an immunostimula= nt, TUBERCIN strengthens a person's own immune system and assists in seeking o= ut and combating cancer cells. HTTD is potentially able to develop TUBERCIN into = a low-cost product to treat cancer patients on an international scale. Salie= nt treatment, through the administration of TUBERCIN, could positively affect= thousands of lives in North America. In addition, Europe and Asia have mil= lions of lives at risk each year because of viral diseases such as cancer.


TUBERCIN IS A FINISHED PRODUCT. Tubercin as an inmunostimulant has been administered to human patients in stages three and four of terminal cancer= There have been no indications of any adverse side effects in human trials= There has been encouraging results of patients with TUBERCIN in the last fourteen years. Various forms of cancer were involved and many of the pati= ents survived.


A review of clinical studies indicate TUBERCIN has no side effects and cou= ld possibly be administered in conjunction with other such modalities for the= treatment of cancer without any adverse effects. The scientific presumptio= n would be the distinct possibility of a strengthened immunity system and th= e administration of treatment such as chemotherapy at the later stages of tu= mor growth would not be impeded by the weakened condition of the terminal canc= er patient. To this end the Company has been assisted by outside consultants = reviewing the research data and human trials involving TUBERCIN to see specifically whereby incidents of dual treatment produced favorable result= s in terms of moving toward indication of prolongation of the life of the cance= r patient.


There is recognition that morphine is an trusted pain killer, but in total= ity it cannot be said that it has no side effects. In the maintaining of patient = care, there is the strong possibility that TUBERCIN could be also considered as = a candidate for a pain management. The Company's scientists describe TUBERCI= N as having the high propensity of deadening the nerve endings in specific area= s where cancer has caused erosion and consequently much pain.



PATENTS

Presently, HTTD has the patent rights for Korea, Japan and the United Stat= es. The Korean patent was issued on October 29, 1998 (Registration No. 173362)= The Japanese patent was issued on June 12, 1998 (Registration No. 2790447). Th= e United States patent was issued on August 14, 2001 (Registration No.6,274,= 356). Currently, patents are pending for Canada and Europe (the United Kingdom, = France, Germany, Italy and Spain).



CANCER IN OUR TIME

In the 20th century, the number of cancer patients has been on the rise. Although many anti-cancer agents were developed and an enormous study on i= ts essence continued, the mortality by cancer still is on the rise. Mankind m= ay be chronically threatened with cancer in the 21st century. Nine million new c= ase of cancer occur annually and five million people die from breast cancer, repo= rts the World Health Organization. Dramatic rises in life expectancy and chang= e in lifestyle are estimated to increase the number of new cancer cases to 20 m= illion annually by 2020 and cancer deaths to more than 10 million.

About 552,200 Americans - more than 1,500 people a day - are excepted to d= ie of cancer this year. In the United States, one of every four deaths is attrib= uted to cancer. Cancer is the second-leading cause of death in the United State= s. Exceeded only by heart disease. About 5 million lives have been lost to ca= ncer since 1990 and about 13 million new cases have been diagnosed. In 2000, mo= re then 1.2 million new cancer cases are expected to be diagnosed. The number= of cancer cases will continue to grow, spurred by the aging population. By 20= 09, tese patients could total 8.4 million. In 1997, about 6.3 million people worldwide died from some form of cancer, and most major international canc= er agencies expect this number to double by 2022.


Please note that HTDS had absolutley nothing to do with this report and is= not a participant in any way.


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This report is based on Stock-Market Spotlight's independent analysis but = also relies on information supplied by sources believed to be reliable. This re= port may not be the opinion of HTDS management. This report should be considere= d biased and contains usually only positive statements regarding the feature= d company. Stock-Market Spotlight does not own or will not purchase HTDS com= mon shares in the open market. The information contained in this report shall = not constitute, an offer to sell or solicitation of any offer to purchase any = security. Penny stocks are considered to be highly speculative and may be = unsuitable for all but very aggressive investors. It is intended for infor= mation and entertainment only. Some statements may contain so-called "forwar= d-looking statements". Many factors could cause actual results to differ. Inves= tors should consult with their Investment Advisor concerning HTDS. This newsletter was= written and distributed for a 4000 dollar fee paid by a third party HTDS shareholder who is purported to have a large stock position in the feature= d company. It is unknown to Stock-Market Spotlight whether this shareholder = intends to sell any or all of his stock position in the featured company. = Copyright 2004 Stock-Market Spotlight. All Rights Reserved.


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