Dear Jmol Users In our research group we have developed a web application to simulate a nanowire based biosensor. The application is built around a Jmol applet which allows the user to rotate a protein on a nanowire surface. The charge of the protein affects the current through the wire and this system can thus be used as a sensor. During development we have received strong support from the Jmol community and would like to present the outcome of this effort. We gladly appreciate any feedback or suggestions for improvements. The application is started by entering a PDB identifier and a pH value into the first form. The structure is loaded in overlay with computed pH dependent charges coming from the PROPKA model. On this page, the Jmol applet can be used to view the protein and to define its binding orientation. Upon submission of the form with the parameters, the server computes the expected sensor response. Upcoming improvements include Ajax implementation and the possibility to monitor signal change over pH.
The authors thank the Jmol community for their support. Martin Hediger, Luca De Vico, Jan Jensen ------------------------------------------------------------------------------ Live Security Virtual Conference Exclusive live event will cover all the ways today's security and threat landscape has changed and how IT managers can respond. Discussions will include endpoint security, mobile security and the latest in malware threats. http://www.accelacomm.com/jaw/sfrnl04242012/114/50122263/ _______________________________________________ Jmol-users mailing list [email protected] https://lists.sourceforge.net/lists/listinfo/jmol-users
