Thanks to everyone for this thread. I've learnt a lot and it gives me some good info about whether to use DNA to search for ancestors.

Thanks again.

Foxy

----Original Message Follows----

OK, I was a bit rushed in writing and did not state the x and y chromosome part quite correctly.

But you are absolutely wrong when you state that a man's x-sperm are all alike and his y-sperm are all alike. You are leaving out the "shuffling" that takes place between *all* the other chromosome pairs except for the x and y. Only the x chromosomes in the "x-sperm" are alike, and the y-chromosomes in the "y-sperm". But *all* the other 22 chromosomes are most likely unique. Each pair of chromosomes in the sexual cells swaps bits and pieces of the chromosomes *before* they separate and the sperm cells are formed with one-each of the 22 chromosomes and either an x or a y chromosome. Same goes for the 23 pairs that the female has - they swap pieces before separating to form the egg cells. (I'm skipping a couple of details here). So there is perhaps *slightly* more variability from the female side than the male, but I'd hardly think that the ratio of 23 to 22 is terribly significant.

But to get somewhat back on-topic: a male's ancestry can be compared with another male's, since the y chromosome, except for mutations, *is* unchanged. So if you are a descendant in the male line from some ancestor, you will have the exact same y chromosome as all other male-line descendants of the same ancestor. Trouble is, this doesn't eliminate possibilities like a *different* male descendant having been the father of a child somewhere along the line. Like: was it Thomas Jefferson or his brother's son(s) who fathered Sally Hemmings' children - no way to tell from the genes.

There are also some other things in human cells that get passed from generation to generation. These are called mitochondria or mitrochondrial DNA. They are handed down *only* in the egg cell from the mother, and also don't change except for mutations. So men never pass them on. But the mitrochondrial DNA can be compared with anyone else's who is also descended in the *female* line (except for the last generation, which may be female > male) from a common ancestor.


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