Teman-teman, 

Ini info lanjutan tentang jagung dan ikan transgenic

Dear Friends.

further news on transgenic fish and bt corn.


----------
> 
> Date: Sunday, December 05, 1999 8:35 PM
> 
> about:
> 1.  New study on Bt: Bt-toxin from transgenic maize seeps into soil
> 2. Risks fom transgenic fish
> 
> 
> 
> 
> 1.    Insecticide from GM corn seeps into soil - study
> 
> Wednesday, Dec 1
> 
> LONDON, Reuters [WS] via NewsEdge Corporation : American scientists said
on
> Wednesday they had uncovered what could be either a potential hazard, or
> benefit, of genetically modified corn.
> 
> Dr Guenther Stotzky and researchers at New York University have shown
that
> BT corn, the seed variety which is resistant to corn borer pests,
releases
> an insecticide through its roots into the soil.
> 
> The toxin remains in the soil as it is not easily broken down. It retains
> its insecticide properties which could help to control pests or promote
> insects resistant to the pesticide -- the scientists aren't sure which.
> 
> ``Further investigations will be necessary to shed light on what might
> happen underground,'' Stotzky and his colleagues said in a report in the
> science journal Nature.
> 
> Their work is the first to show that the toxin from the
> genetically-engineered BT corn can seep into the soil.
> 
> .......
> THE TIMES THURSDAY DECEMBER 2 1999   _______
> 
> GM crop toxin is leaking into the soil
> 
> BV NICK NUTTALL  ENVIRONMENT CORRESPONDENT
> 
> SOME genetically modified crops are leaking powerful tox- ins from their
> roots into the soil, scientists have found.
> 
> Researchers described the findings as "surprising and un- expected",
> raising fresh fears about the environmental im- pact of such crops.
> 
> Companies have modified plants to produce poisons or toxins to combat the
> pests that eat their stems and leaves. But the discovery that the same
> plants are also leaking toxins into the soil has not, until now, been
> considered an issue.
> 
> It will raise fears among some scientists, regulators and environmental
> groups that beneficial soil organisms might be killed and that in- sects
> living in the soil might be- come resistant to the poisons.
> 
> The findings, published to- day in Nature, have been re- leased by a team
> at the Univer- sity of New York that has been studying the roots of GM
> maize.
> 
> Several crops, from maize, to corn and potatoes, have been genetically
> modified to kill insect pests using a gene derived from a bacterium
called
> Bacillus thuringiensis (BT). In the United States 15 million acres of
corn
> modified with the BT gene were planted in 1998 or just under 20 per
> 
> cent of the total crop. GM maize has also been planted in Europe although
> the acreage is far smaller.
> 
> Concerns about the impact of such crops on the environ- ment were
triggered
> earlier in the year when it was found that monarch butterflies had died
> after feeding on milk- weed dusted with pollen from GM corn.
> 
> Other research found that lacewings that had fed on corn borers reared on
> BT corn had also died, raising concerns that such crops are harming more
> than just pests.
> 
> Professor Guenther Stozky, of New York University's labo- ratory of
> microbial ecology, who has led the research, said yesterday that the
> monarch re- search showed that the toxin was released from the pollen.
> 
> "Now we have found it is also continuously released from the roots into
the
> soil. The fact that the toxin is re- leased from the roots was unex-
> pected," he said.
> 
> Professor Stozky said that the BT toxin was a large pro- tein molecule
> which they had considered too large to cross the root membrane.
> 
> During the research, the team grew GM seedlings in the laboratory for 25
> days. Each plant produced on aver-
> 
> age 105 microgrammes of pro- tein and this was tested against larvae of
the
> tobacco hornworm. Up to 95 per cent of the larvae died after five days
with
> 50 per cent killed at a dose of just 5.2 micro- grammes of protein.
> 
> Because the roots are con- stantly leaking the toxin, there is also the
> risk that pests in the soil might rapidly become im- mune to the poison
> triggering new, resistant, strains.
> 
> 
> Here are some comments by Dr. Charles Benbrook, former Director of the
> Board on Agriculture of the US Academy of Science:
> 
> Nature Article re Bt Exudates in Soil
> 
> The December 2, 1999 Nature contains a brief communication entitled
> "Insecticidal toxin in root exudates from Bt corn," by Saxena, Flores and
> Stotsky, researchers at New York University (full copy in PDF available
> from Nature at
> <http://www.nature.com/server-java/Propub/nature/402480A0.pdf>.  (We will
> also post it on Ag BioTech InfoNet under "Environmental Impacts, "Soil
> Systems," along with this commentary).
> 
>       This report is not likely to generate the attention received by the
> much-debated Losey et al. Nature article on Bt-pollen and Monarchs,
> although it certainly should.
> 
>       In a nutshell, the new report finds that a common current
> Bt-transgenic corn variety exudes Bt toxin through root exudates --
> actually, this finding comes as no great surprise, just as the Losey et
al.
> finding that Bt corn pollen can kill Monarchs was not a surprise.  But
the
> new report and research documents that the activated Bt toxin is exuded
> through roots, binds with soil particles, becomes very stable --
persisting
> in the soil for 243 days, and that it remains active (i.e. toxic) to soil
> insects for very long periods.  Hence, Bt toxin from root exudates will
be
> augmented by toxin in residues from corn plant residues later in the fall
> and winter.
> 
>       The implications of the findings reported in the new article are
> largely unknown but could be enormous.  Bt comes from a common soil
> bacterium; to the extent that Bt-transgenic crops significantly enhance
the
> quantity of a particular toxin in soil, there will be impacts on other
soil
> microorganisms and soil microbial communities.  These impacts will, in
turn
> effect nutrient cycling and uptake, microbial biocontrol of soil
pathogens,
> and perhaps the development and triggering of the corn plant's immune
> system.  As the authors point out, some of the effects are likely to
prove
> positive and some negative.
> 
>       These impacts may be transitory and insignificant; it is likely
> they will be major in some soils and systems and not in others; they may
> prove short-lived and highly cyclic, or they may build overtime, reaching
a
> point in some fields where major and sustained shifts occur in soil
> microbial communities.  They may prove modest compared to the impact of
> tillage; they may reinforce some of the adverse impacts of tillage, or
> actually prove a bigger problem in no-till systems.
> 
>       The second reason that the paper is so important is that the next
> major EPA review of a GMO corn is about to get underway, with commercial
> introduction planned for crop season 2002, if regulatory approvals are
> received in time.  The new variety is being developed by Dow AgroSciences
> in cooperation with Pioneer and has been engineered to express a Bt toxin
> in corn root systems and exudates at levels high enough in order to
control
> the corn rootworm complex, by far the toughest, nastiest set of insect
> pests corn farmers have to manage.
> 
>       Resistance management will again be a major concern, and again the
> high dose strategy will almost certainly be a cornerstone of the strategy
> deployed and the evidence advanced by the company in support of approval.
> There has been no public discussion or scientific community appraisal of
> what a Bt-toxin  "high dose" for corn rootwrom management will be, but
rest
> assured it will be two or more orders of magnitude higher than the levels
> analyzed in the just published Nature piece.
> 
>       Proponents of the new Bt-corn technology will correctly point out
> that corn rootworms are damaging pests in second year corn fields (i.e. a
> field planted to corn two or more years in a row).  In most parts of the
> corn belt, rotation with soybeans remains an effective cultural practice
> that lies at the heart of corn rootworm IPM systems, and has for 30
years.
> But the plot has thickened in recent years -- a new strain or subspecies
of
> the western corn rootworm has adapted around rotation and is causing
> economic damage in some first year corn fields in parts of the corn belt.
> Its range is expanding every year and insecticide applications for corn
> rootwrom control are clearly rising. (For a detailed discussion of this
> adaptation and overview/references/links to key University of Illinois
> research on this new problem, see Section D, "Evolving Insect Pest
> Challenges," page 17 in the January 1999 paper "World Food System
> Challenges and Opportunities: GMOs, Biodiversity, and Lessons from
> America's Heartland," accessible at
<http://www.biotech-info.net/IWFS.pdf>).
> 
>       Until recently, most of the soil insecticides used to control corn
> rootworms have met everyone's definition of nasty.  Highly toxic
carbamate
> and organophosphate insecticides accounted for the lion's share of acres
> treated and pounds applied.   Most farmers hate handling these
> insecticides; they pose significant risks to birds, fish, pets, and a
range
> of beneficial organisms.  In the last two years, two much safer new
> insecticides have come on the market.  A synthetic pyrethroid product
> marketed by Zeneca called Force (active ingredient, tefluthrin) is
getting
> rave reviews by farmers and may soon emerge as the product of choice. 
From
> an environmental perspective, it is far, far less damaging than the OP
and
> carbamate insecticides it is replacing.
> 
>       EPA's review and approval decision on the new Bt-corn for rootwrom
> control is going to really put the agency to the test.  Without a doubt,
> there will remain major unresolved issues regarding resistance management
> and soil microbial community and plant health impacts.  In addition,
there
> will be major debates about the actual "benefits" of the technology in
> light of the availability of cost-effective alternatives.
> 
>       In the meantime and hopefully prior to approval, information is
> needed on the exact toxin expressed in roots; the level of expression and
> the temporal dynamics of expression, along with levels in plant tissue
and
> residues; its fate in soil ecosystems under different tillage and
planting
> systems; the impact of the Bt toxins on various beneficial and pathogenic
> soil microorganisms and arthropods/decomposers.  This information will be
> among that needed in order to determine whether this technology might
lead,
> on balance, to sustained and significant adverse impacts on soil quality
> and plant health.
> 
>       As the authors state, what goes on underground in a field planted
> to today's Bt-corn varieties is largely a mystery.  Enhance the toxin
> levels 100- to 1,000-fold and it becomes a mystery of some consequence
and
> immediacy.
> 
>               chuck benbrook
> 
> 
> 
> Charles Benbrook                          CU FQPA site
www.ecologic-ipm.com
> Benbrook Consulting Services    Ag BioTech InfoNet www.biotech-info.net
> 5085 Upper Pack River Road      IPM site www.pmac.net
> Sandpoint, Idaho 83864
> 208-263-5236 (Voice)                   208-263-7342 (Fax)
> 
> 
> 
> 2. Transgenic fish
> 
> Wednesday December 1, 12:01 AM
> 
> Source: Proceedings of the National Academy of Sciences (vol 96, p 13
853)
> (From New Scientist <http://www.newscientist.com>, 4/12/99)
> 
> Today's News
> 
> Could one genetically modified fish invade a species and destroy it?
> 
> By Matt Walker
> 
> A SINGLE genetically modified fish could turn Darwinian evolution upside
> down and wipe out local populations of the species if released into the
> wild, biologists warn. They add that other organisms could face the same
> risk from transgenic relatives.
> 
> William Muir and Richard Howard of Purdue University in West Lafayette,
> Indiana, made the discovery while modelling ecological risks associated
> with genetically modified organisms (GMOs). They have dubbed their idea
the
> "Trojan gene" hypothesis. "This resembles the Trojan horse," says Muir.
"It
> gets into the population looking like something good and it ends up
> destroying the population.".
> 
> The researchers studied fish carrying the human growth hormone gene hGH,
> which increases growth rate and final size. Biologists in the US and
> Britain are experimenting with salmon engineered in a similar way,
although
> no one has yet begun commercial production.
> 
> Muir and Howard included hGH in embryos of a fish called the Japanese
> medaka (Oryzias latipes), a common aquarium fish that is widely used in
> research. They found that modified individuals became sexually mature
> faster than normal fish and produced more eggs.
> 
> Other experiments using non-modified fish also showed that larger males
> attracted four times as many mates as their smaller rivals. This effect
is
> also known in salmon. Muir predicts that bigger, engineered fish would
> enjoy the same advantages. So the hGH gene would quickly spread through a
> fish population.
> 
> But Muir and Howard also found that only two-thirds of engineered medaka
> survived to reproductive age compared with wild medakas. So the spread of
> the growth hormone gene could make populations dwindle and eventually
> become extinct.
> 
> To quantify this, the researchers plugged their results into a computer
> model to find out what would happen if 60 transgenic individuals joined a
> wild population of 60 000 fish. The population became extinct within just
> 40 generations. Even a single transgenic animal could have the same
effect,
> they found, although extinction would take longer.
> 
> "You have the very strange situation where the least fit individual in
the
> population is getting all the matings--this is the reverse of Darwin's
> model," says Muir. "The sexual selection drives the gene into the
> population and the reduced viability drives the population to
extinction."
> The researchers say their results are the first evidence that GMOs could
> have catastrophic consequences on their own species.
> 
> 
> 

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