https://www.economist.com/science-and-technology/2020/07/22/the-hunt-for-the-origins-of-sars-cov-2-will-look-beyond-china


> The virus may have been born in South-East Asia

> ONE OF THE great questions of the past six months is where SARS-CoV-2, the 
> virus that causes covid-19, came from. It is thought the answer involves 
> bats, because they harbour a variety of SARS-like viruses. Yunnan, one of 
> China’s southernmost provinces, has drawn the attention of virus hunters, as 
> the closest-known relatives of SARS-CoV-2 are found there. But some think the 
> origins of the virus are not to be found in China at all, but rather just 
> across the border in Myanmar, Laos or Vietnam.
> 
> This is the hunch of Peter Daszak, head of EcoHealth Alliance, an 
> organisation which researches animals that harbour diseases that move into 
> people. Since the outbreak, in 2003, of the original SARS (now known as 
> SARS-CoV), scientists have paid close attention to coronaviruses. Dr Daszak 
> says that around 16,000 bats have been sampled and around 100 new SARS-like 
> viruses discovered. In particular, some bats found in China are now known to 
> harbour coronaviruses that seem pre-adapted to infect people. The chiropteran 
> hosts of these viruses have versions of a protein called ACE2 that closely 
> resemble the equivalent in people. This molecule is used by SARS-like viruses 
> as a point of entry into a cell.

....

> Support for the idea that something resembling SARS-CoV-2 might have been 
> circulating in the region before the pandemic began also comes from another 
> intriguing observation: the low incidence of covid-19 in South-East Asia, 
> particularly in Vietnam. John Bell, a professor of medicine at the University 
> of Oxford, says everyone thought there would be a flood of cases in Vietnam 
> because the country is right across the border from China. Yet Vietnam has 
> reported only 300 in a population of 100m, and no deaths. The country did not 
> have a great lockdown either, he adds. Nobody could work out what was going 
> on.
> 
> One explanation, he suggests, is that Vietnam’s population is not as 
> immunologically “naive” as has been assumed. The circulation of other 
> SARS-like viruses could have conferred a generalised immunity to such 
> pathogens. So, if a new one emerged in the region, it was able to take hold 
> in the human population only when it travelled all the way to central 
> China—where people did not have this natural resistance.


-- 
Kim Holburn
IT Network & Security Consultant
T: +61 2 61402408  M: +61 404072753
mailto:[email protected]  aim://kimholburn
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