I think you might be missing Paul's point. While yes I use KDE on both the Solaris side and the Linux side everyday, not everyone does. By using the KDE libraries you lock yourself into someone using a system that has KDE. If I were building a standalone system that only did music applications I would NOT use KDE. Not for an integrated system, there is just way to much overhead (have you seen the memory it uses).
What I think is trying to be conveyed is that by using just a GUI Toolkit you allow your application to be open to any desktop environment and therefore allow it to be used across the entire spectrum. It's more helpful advise than anything else. Look at it this way. If person A writes their application for Gnome and person B writes their application for KDE and both are dependent on the Desktop environment, someone who loves both programs is going to either have to just pick one or port one. This is why taking the desktop out of the equation is so important for making linux a very powerful music workstation OS where you have the ultimate in usability and customization. Just me 2 cents. Rick