The config has been running since over an year. So I am sure it is nothing to 
do with the configuration. 

Log files are also rotated on daily basis. 
Even upgraded clamav installation, cleared olb DB with new one, etc.. 

There was permission issue with /var/clamav which I resolved before posting 
here. 

In between another server too faced the same issue but it mentioned 
out-of-memory issue in the message log file. I tried a few things but didnt 
work. I saw that swap space was being used. And finally I decided to restart 
the server. 

After restart that server all is well so far. 
I did fire fighting with the server that did not complain of memory issue. In 
the end I restarted that as well. That too is working fine now!  :(  no clue 
how to get over this issue without restarting!  

I am posting another topic to know how to deal with swapping and free swap 
space if memory is available.

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