I do not use Preview but I understand that there are issues with Preview under Yosemite which require to interact twice before you can access the text.
A thing to try, if your wife can see the text, is to print the file, oddly to PDF. The OS X print dialogue allows you to print to PDF and this may result in another PDF file which is more friendly to Voiceover. Make sure it you give another file name. Alternatively Do you have access to Nisus Writer Pro? This is a paid app but I use it on the mac to read PDF. If the PDFs are inaccessible because they are either graphics or DRM protected you may have to use something like Finereader to access them. David Griffith <--- Mac Access At Mac Access Dot Net ---> To reply to this post, please address your message to mac-access@mac-access.net You can find an archive of all messages posted to the Mac-Access forum at the list's public Mail Archive: <http://www.mail-archive.com/mac-access@mac-access.net/>. Subscribe to the list's RSS feed from: <http://www.mail-archive.com/mac-access@mac-access.net/maillist.xml> As the Mac Access Dot Net administrators, we always strive to ensure that the Mac-Access E-Mal list remains malware, spyware, Trojan, virus and worm-free. However, this should in no way replace your own security strategy. We assume neither liability nor responsibility should something unpredictable happen. Please remember to update your membership preferences periodically by visiting the list website at: <http://mail.tft-bbs.co.uk/mailman/listinfo/mac-access/options/>