I am unable to reply Mailman Administrator , how best can i fix this problem 
the output i get is below


The message WAS NOT relayed to:<n...@domain name>:
[127.0.0.1] said:554 5.4.0 Failed, id=21662-04, from MTA([127.0.0.1]:10025):
554 5.4.0 Error: too many hops
 
This nondelivery report was generated by the program
amavisd-new at host mail.mak.ac.ug. Our internal reference code for your
message is 21662-04/EUHGsEqR1cWQ
 
Undeliverable mail MTA blocked


My smtp-failure mailman logs show the output below:

Low level smtp error: [Errno111] Connection refused, msgid:  
<mailman.0.1272542181.3599....@muklists.mak.ac.ug>delivery
to a...@dicts.mak.ac.ug failed with code -1: [Errno 111] Connection refused



      
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