SARS-2 is a RNA virus. <https://en.wikipedia.org/wiki/RNA_virus>With high mutation rates and short generation times, these acute infections typically evolve like wild. It happens that the betacoronaviruses <https://en.wikipedia.org/wiki/Betacoronavirus>also have a "spellchecker" or "proofreader" <https://www.nature.com/articles/s41579-020-00468-6> that often corrects such mutations.

That inherent characteristic hardly puts us in the clear, however, if the present pandemic doesn't offer us pause enough.

As we approach anything from <https://www.medrxiv.org/content/10.1101/2020.07.07.20148460v2>50 to 500 million people infected, a variety of strains are likely to emerge. Most mutations that the spellchecking misses will have little effect or make matters /worse /for the virus. But we're trafficking in such numbers that rare improvements from the virus's vantage point bend toward inevitable.

The worry about the resulting fallout is two-fold:

That the strains will engage in what's called "interdemic selection". <https://dragonflyissuesinevolution13.wikia.org/wiki/Interdemic_selection> The various strains emerging might compete at the level of host population until one beats all the rest and spreads out again from its point of origin, out from underneath whatever herd immunity we develop—natural or vaccine-derived.

https://www.patreon.com/posts/45306108



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