Hi Adrian, if you need low level access there is a python wrapper of the 
MINUIT and MINUIT2 fitting libraries : 
http://code.google.com/p/pyminuit/ and http://code.google.com/p/pyminuit2/
It is targeted primarily toward High Energy Physics people, most of whom 
are familiar with the MINUIT library, but it would solve your problem as 
well. The doc is still lacking in the project, as I do not have much 
time, so feel free to ask me questions about it or even to send me some 
files so that I can try out to script the fit on my side (I work in the 
field of astro-particle physics and astrophysics, so I might even be 
interested in the context of your problem!) .

best,
Johann

Adrian Price-Whelan wrote:
> Hey guys -
>
> I'm working on a Histogram of pixel values from an astronomical image  
> that looks like a Gaussian curve and then polynomial decay.  I'm  
> trying to figure out a way to fit a Gaussian regression to the  
> histogram, but can't find any documentation on this. thanks!
>
> -adrian
>
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