Hello Robert, some responses below...

Ingraham, Robert wrote:
>
> I am trying run mauve using a Linux platform, it ‘hangs up” after 
> about 15 minutes. This is my fifth attempt, is there anything obvious 
> I am doing wrong?
>
> I am using a FASTA multi file as input.
>
> This is the command line file:
>

<snip>
>
> /share/apps/mauve/mauve_2.1.1/linux-x64/progressiveMauve --seed-family 
> --seed-weight=19 --output=/home/RGIngraham/Clostridia_10a 
> --backbone-output=/home/RGIngraham/Clostridia_10a.backbone 
> --output-guide-tree=/home/RGIngraham/Clostridia_10a.guide_tree 
> /home/RGIngraham/Clostridia_10.mfa.txt
>
> This is the output:
>
<snip>

> Creating sorted mer list
>
> Create time was: 1 seconds.
>
> 0%..1%..2%..3%..4%..5%..6%..7%..8%..9%..10%..
>
> 11%..12%..13%..14%..15%..16%..17%..18%..19%..20%..
>
> 21%..22%..23%..24%..25%..26%..27%..28%..29%..30%..
>
> 31%..32%..33%..34%..35%..36%..37%..38%..39%..40%..
>
> 41%..42%..43%..44%..45%..46%..47%..48%..49%..50%..
>
> 51%..52%..53%..54%..55%..56%..57%..58%..59%..60%..
>
> 61%..62%..63%..64%..65%..66%..67%..68%..69%..70%..
>
> 71%..72%..73%..74%..75%..76%..77%..78%..79%..80%..
>
> 81%..82%..83%..84%..85%..86%..87%..88%..89%..90%..
>
> 91%..92%..93%..94%..95%..96%..97%..98%..99%..done
>
> waiting
>

The "indefinite waiting" phenomenon was a bug specific to the linux 
64-bit build of progressiveMauve 2.1.1. For reference, this bug was also 
described in the following mailing list thread:
http://www.mail-archive.com/[email protected]/msg00035.html

Until a new progressiveMauve release can be made, the best workaround 
for 64-bit linux is to use the 2.0.0 build available here:
http://gel.ahabs.wisc.edu/mauve/downloads/misc/progressiveMauve_2.0.0_linux_x64_ghostfix.tar.gz

Another hint is that you will need to remove the --seed-family option as 
it was introduced in 2.1.0 and thus is not compatible with the 2.0.0 
release.


Hope that helps,
-Aaron


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