When in college there was this girl at my church who had a crush on me (or at 
least she acted like she did).    I had my own dorm room and I am sure I 
could've...um...taken advantage of the situation.  We dated for a few months, 
but I broke it off the day after Xmas that year.

The thing was she had a distinctive scent that just turned me off.  It wasn't 
that she stunk or didn't have good hygeine; I just wasn't that much attracted 
to her even though she was physically attractive.  At the time, I chalked it up 
to my religious ethics of not taking advantage of someone for whom I had no 
feelings, yet the "smell factor" has always...er...lingered in my olfact...,no, 
mind.

What catches my attention about this abstract is that the MHC pushes animals 
towards heterozygosity or heterogeny.  Keeping the appropriate amount of 
genetic (allelic) variation within populations is crucial for the survival of 
that group.  In addition to avoiding the weakness and defects found in inbred, 
homozygous individuals within a group, it provides  sufficient mutant or 
more-varied strains at either end of the population distribution that aids in 
survival from selective pressures presented by conditions.

Also, I think we are often influenced in our choices in life by unseen forces.  
No, not the  divine, but rather biological pressures that we are mundanely 
unaware of and that we attribute to our conscious deliberation or thought.  
Still, we must go through life thinking we are in control even though the 
currents around us determine our course more than our visible compass.

Preston
  ----- Original Message ----- 
  From: CrossBow 
  To: Memphis Freethought Alliance 
  Sent: Friday, December 05, 2008 10:26 AM
  Subject: Major Histocompatibility Complex Alleles, Sexual Responsivity, and 
Unfaithfulness in Romantic Couples


  That "Smell Factor" again...

  Major Histocompatibility Complex Alleles, Sexual Responsivity, and 
Unfaithfulness in Romantic Couples

  Copyright Copyright © 2006 Association for Psychological Science
  ABSTRACT
  ABSTRACT—Preferences for mates that possess genes dissimilar to one's own at 
the major histocompatibility complex (MHC), a polymorphic group of loci 
associated with the immune system, have been found in mice, birds, fish, and 
humans. These preferences may help individuals choose genetically compatible 
mates and may adaptively function to prevent inbreeding or to increase 
heterozygosity and thereby immunocompetence of offspring. MHC-dissimilar mate 
preferences may influence the psychology of sexual attraction. We investigated 
whether MHC similarity among romantically involved couples (N= 48) predicted 
aspects of their sexual relationship. All women in our sample normally 
ovulated, and alleles at three MHC loci were typed for each person. As the 
proportion of MHC alleles couples shared increased, women's sexual responsivity 
to their partners decreased, their number of extrapair sexual partners 
increased, and their attraction to men other than their primary partners 
increased, particularly during the fertile phase of their cycles.

  and...
  Birth Control Pills Affect Women's Taste in Men
  How synthetic hormones change desire in women--and their choice in a mate
  By Melinda Wenner 

  This year 2.25 million Americans will get married—and a million will get 
divorced. Could birth control be to blame for some of these breakups? Recent 
research suggests that the contraceptive pill—which prevents women from 
ovulating by fooling their body into believing it is pregnant—could affect 
which types of men women desire. Going on or off the pill during a 
relationship, therefore, may tempt a woman away from her man.
  It's all about scent. Hidden in a man's smell are clues about his major 
histocompatibility complex (MHC) genes, which play an important role in immune 
system surveillance. Studies suggest that females prefer the scent of males 
whose MHC genes differ from their own, a preference that has probably evolved 
because it helps offspring survive: couples with different MHC genes are less 
likely to be related to each other than couples with similar genes are, and 
their children are born with more varied MHC profiles and thus more robust 
immune systems.

  A study published in August in the Proceedings of the Royal Society B, 
however, suggests that women on the pill undergo a shift in preference toward 
men who share similar MHC genes. The female subjects were more likely to rate 
these genetically similar men's scents (via a T-shirt the men had worn for two 
nights) as pleasant and desirable after they went on the pill as compared with 
before. Although no one knows why the pill affects attraction, some scientists 
believe that pregnancy—or in this case, the hormonal changes that mimic 
pregnancy—draws women toward nurturing relatives.

  Women who start or stop taking the pill, then, may be in for some 
relationship problems. A study published last year in Psychological Science 
found that women paired with MHC-similar men are less sexually satisfied and 
more likely to cheat on their partners than women paired with MHC-dissimilar 
men. So a woman on the pill, for example, might be more likely to start dating 
a MHC-similar man, but he could ultimately leave her less sexually satisfied. 
Then if she goes off the pill during the relationship, the accompanying 
hormonal changes will draw her even more strongly toward more MHC-dissimilar 
men. These immune genes may have a "powerful effect in terms of how well 
relationships are cemented," says University of Liverpool psychologist Craig 
Roberts, co-author of the August paper.

  Note: This article was originally published with the title, "A Tough Pill to 
Swallow".




  -- 
  gnothe se auton


  

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