Long time without a post! Given info from US FDA on size of phase 3 clinical trials the Pfizer study is a close second to J&J. Phase 3 is the last step to collect data before one could apply for clearance to use in the US:
Pfizer: 43.651 (Combined phase 2/3) https://www.fda.gov/media/144416/download (Table Moderna: 30,418 https://www.fda.gov/media/144434/download (Table 1) J&J/Janssen: 44.325 https://www.fda.gov/media/146217/download (Table 5) While the Pfizer study was a combined phase 2/3 study (w/FDA blessing), phase 2 studies are relatively small- for example, ~2k people in the Moderna Phase 2. If you have good data and are addressing an urgent need you can ask FDA to combine a phase 2 and phase 3. If they like your data, they're likely to give you the green light. While not common, this approach has been used with previous disease states and drugs. I'll echo what was said before- if you can get a shot, take what you can get. The differences in efficacy are minor compared to the risk of covid...esp w/the new variants swimming around. Tony Wirtel ...still Benzless On Fri, Mar 12, 2021 Kaleb Striplin wrote > To: Mercedes Discussion List <mercedes@okiebenz.com> > Subject: Re: [MBZ] OT - COVID Vaccine > Message-ID: <17918ba0-945d-4369-80af-5e9f34b56...@striplin.net> > Content-Type: text/plain; charset=utf-8 > > I think that Pfizer one was tested on a very small sample which determined > its effectiveness and the moderna was more fully tested, or so I was told. > > Sent from my iPhone > > > On Mar 12, 2021, at 7:18 AM, Dan Penoff via Mercedes < > mercedes@okiebenz.com> wrote: > > > > ?I?ll take what they?re giving, as long as it works. A couple of > percentage points either way isn?t going to make a difference. > > > > -D > > > >> On Mar 12, 2021, at 8:15 AM, Buggered Benzmail via Mercedes < > mercedes@okiebenz.com> wrote: > >> > >> Either one is fine > >> > >> --FT > >> Sent from iPhone > >> > _______________________________________ http://www.okiebenz.com To search list archives http://www.okiebenz.com/archive/ To Unsubscribe or change delivery options go to: http://mail.okiebenz.com/mailman/listinfo/mercedes_okiebenz.com
