*University of Utah (U of U) medical researchers have uncovered a wiring
diagram that shows how the brain pays attention to visual, cognitive,
sensory, and motor cues. The research provides a critical foundation for the
study of abnormalities in attention that can be seen in many brain disorders
such as autism, schizophrenia, and attention deficit disorder. (Credit:
iStockphoto/Sebastian Kaulitzki)*



*November 3, 2010*

*ScienceDaily* — The study appears Nov. 1, 2010, online in the Proceedings
of the National Academy of Sciences (PNAS).

"This study is the first of its kind to show how the brain switches
attention from one feature to the next," says lead researcher Jeffery S.
Anderson, M.D., Ph.D., U of U assistant professor of radiology. Anderson and
his team used MRI to study a part of the brain known as the intraparietal
sulcus. "The brain is organized into territories, sort of like a map of
Europe. There are visual regions, regions that process sound and areas that
process sensory and motor information. In between all these areas is the
intraparietal sulcus, which is known to be a key area for processing
attention," Anderson says. "We discovered that the intraparietal sulcus
contains a miniature map of all of these territories. We also found an
organized pattern for how control regions of the brain connect to this map
in the intraparietal sulcus. These connections help our brain switch its
attention from one thing to another."

In addition, scientists discovered that this miniature map of all the things
one can pay attention to is reproduced in at least 13 other places in the
brain. They found connections between these duplicate maps and the
intraparietal sulcus. Each copy appears to do something different with the
information. For instance, one map processes eye movements while another
processes analytical information. This map of the world that allows us to
pay attention may be a fundamental building block for how information is
represented in the brain.

"The research uncovers how we can shift our attention to different things
with precision," says Anderson. "It's a big step in understanding how we
organize information. Furthermore, it has important implications for
disease. There are several diseases or disorders where attention processing
is off, such as autism, attention deficit disorder, and schizophrenia, among
others. This research gives us the information to test theories and see what
is abnormal. When we know what is wrong, we can talk about strategies for
treatment or intervention."

Deborah Yurgelun-Todd, Ph.D., professor of psychiatry in the U of U Schoold
of Medicine and an investigator with the U of U Brain Institute and the Utah
Science Technology and Research Initiative (USTAR), was the principal
investigator and senior author of the study. The research was funded by a
National Institutes of Health grant from the National Institute on Drug
Abuse.

Editor's Note: This article is not intended to provide medical advice,
diagnosis or treatment.

http://www.sciencedaily.com/releases/2010/11/101101151724.htm

*Story Source:*

The above story is reprinted (with editorial adaptations by ScienceDaily
staff) from materials provided by University of Utah Health Sciences, via
EurekAlert!, a service of AAAS.

*Journal Reference:*

Jeffrey S. Anderson, Michael A. Ferguson, Melissa Lopez-Larson, Deborah
Yurgelun-Todd. Topographic maps of multisensory attention. Proceedings of
the National Academy of Sciences, 2010; DOI: 10.1073/pnas.1011616107

http://www.pnas.org/content/early/2010/10/27/1011616107

http://www.pnas.org/content/suppl/2010/10/28/1011616107.DCSupplemental/pnas.201011616SI.pdf

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