It's a known issue with certain builds of perl, please look in the list archives for similar reports.
Several people reported success with max os x using perl built with usethreads enabled. Here is one of them:
http://marc.theaimsgroup.com/?l=apache-modperl-dev&m=105955380011549&w=2
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-- Reporting bugs: http://perl.apache.org/bugs/ Mail list info: http://perl.apache.org/maillist/modperl.html
