This question refers to the proper way to analyze 4-Dimensional data
sets using geometric morphometrics.



The data that I am talking about are a series of 3D data measured from
two different groups at regular time intervals - essentially changing
shapes during growth. The question I would like to address is if the
same types of changes in shape over time occur in both groups. In terms
of a simple bivariate analysis each group can be characterized by
shape/time and the analysis would compare the shape/time slopes between
the two groups. The complication is that "shape" is multivariate
landmark data and that there is no reason to believe that shape change
would have a quasi-linear relationship with time.



So, my question is how to approach these data. Do I conduct a Procrustes
analysis of the entire data set including the time, essentially a
superimposition of 4D data, and compare groups with these numbers -
treating the time value as just another dimension (XYZT coordinates)?
Or, do I conduct a Procrustes superimposition of the 3D landmark data
first and then re-associate them with their time values? Or, is there a
third way to go? The problem here is similar to the setup described by
Dean and Cerney in their Journal of Biomechanics (2007) article,
although I am not entirely certain that their solution applies to this
case. Maybe it does, but right now, it's a little confusing.



I am not sure which way is correct, and I would appreciate the advice of
the group. Either way I go, I see this analysis as a MANOVA with
repeated measures of shape using time as the independent variate. I
would like to be able to set this up as a resampling analysis, but I
can't think how I would do that with a repeated measures design. Again,
any help would be appreciated.



On an aside, I submitted the 4D data as an NT-SYS file to Morpheus, and
it plotted the data just fine. I'm not sure what the plot means (a 2D
summary of a 4D data set), but I thought it was interesting that the
program still did something. Morphologika went the more expected route
and refused to accept 4D data.



Thomas M. Greiner, Ph.D.

Assistant Professor of Anatomy

Dept. of Health Professions

University of Wisconsin - La Crosse

1725 State Street

La Crosse, WI 54601  USA



Phone: (608) 785-8476

Fax: (608) 785-8460







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