I am working on a mysql database with many large tables (1.5 million rows on
some) and came across a beeg problem.

I have need for a query like this:
mysql> select distinct subsnp_pk as sqnmid, c.chrom, chrompos, source as
panel,  null as first_pcrp, null as second_pcrp, null as prb_seq, null as
term,  null as validation, null as freq, null as population  from locuslink
l, subsnp left outer join chromosome_position c  on subsnp_pk = c.snp_fk
left outer join locus_annotation a  on subsnp_pk = a.snp_fk where a.locusid
= substring(l.locusid, 4) and description like '%GABA%' order by subsnp_pk;

Which seems insane.  This 4 table join in another situation would become a 6
table join.  As it is, it takes 1min 10.60 seconds for this query to return
one result.  Clearly I am not a MySQL expert, and even though this query
works, there must be a better way to do this.

Is it a matter of indexing?  A matter of poor schema design?  Poor query
design?  Is it unavoidable?

As far as I know, none of the tables are indexed (I did not set up the
schema).

Please let me know if more info is required to help with this.

Thanks,
Bryan


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