server optimization

[jsmforum]

Hey all,
 
I've got a new server set up, with dual Intel quad core processors, 4 gig of 
ram, OpenSuse 10.3 (64bit) and MySql 5.0.45.  
 
The majority of the tables are MyISAM with a few InnoDB here or there.  I'm 
using the huge-my.cnf as the base for my config.
 
Can anyone suggest some tweeking to the my.conf that will give me the best 
performance on this platform?
 
Thanks,
 
Jeff