Prepared SQL statements - Faster performance?

[mos]

I would like to speed up my Select queries since I'm executing approx 5,000 
of them, same syntax but the search values for 2 columns will change with 
each query. Will I see any performance increase if I prepare the statement 
and use parameters? (I don't need to use the query cache since the result 
set will be returned only once for each set of search values.)

TIA
Mike
MySQL 5.024
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