I use a diode in-series with a power supply (about +160V). If you are a 
purist, you can add some series resistance.

It's not an accurate model but it will get you in the ballpark for most 
designs. It will NOT suffice if you need to model ionization, because that 
happens at a higher voltage than while glowing.
If your design requires a very accurate model of a nixie tube, then I would 
re-examine the circuit because it's too sensitive to varying nixie-tube 
characteristics.


I've plotted  IV curves for all of my b7971 tubes (because of their high 
value) and found that over the proper operating region they are fairly 
linear; the slope representing the resistance of the tube at that point. As 
far as ionization voltage is concerned, it's not easy to measure accurately 
and it varies a lot from tube-to tube. I always use anode supplies above 
200V to allow adequate margin for ionization.

There are models online for NE-2 bulbs which include the effects of higher 
ionization voltage and it's overall non-linear behavior, so you could 
modify it accordingly for a nixie tube.



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