Hi Michael,

Thanks for your response. I was able to solve the problem by installing latest 
version of Ubundu 11.10. NESSY works fine on this version. I really appreciate 
your help. 

Dhanas

On Jan 15, 2012, at 3:22 PM, [email protected] wrote:

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>   1. Re: Nessy-users Digest, Vol 9, Issue 3 (Michael Bieri)
> 
> 
> ----------------------------------------------------------------------
> 
> Message: 1
> Date: Mon, 16 Jan 2012 09:22:12 +1100
> From: Michael Bieri <[email protected]>
> Subject: Re: [Nessy-users] Nessy-users Digest, Vol 9, Issue 3
> To: [email protected]
> Message-ID: <[email protected]>
> Content-Type: text/plain; charset="iso-8859-1"; Format="flowed"
> 
> Hi Dhanas
> 
> This is a very strange error. Are you using the default theme of Ubuntu? 
> I am not sure if this is a NESSY problem, as NESSY uses the system font 
> of the operating system, and so far, there was no problem on Ubuntu, 
> Fedora, Windows or Mac with the font. Could you solve this problem?
> 
> Cheers
> Michael
> 
> 
> Am 14.01.2012 06:50, schrieb Dhanasekaran Muthu:
>> Hi Michael,
>> 
>> Thanks for the information.  I was able to get the plots the way I 
>> wanted. I wanted to try the NESSY on Ubuntu now. I have installed 
>> Ubuntu on my mac using virtual box.  I downloaded the 
>> NESSY.11.12.1.Deb.32bit version. When I try to run the program by 
>> ./nessy command, I get the GUI interface but the fonts are looking not 
>> right. I have attached the screen shot for your reference. The error 
>> is (nessy:3900) Pango-Warning **: failed to choose a font, expect ugly 
>> output ...... It seems Pango is already in the Ubundu. Do you have any 
>> idea what is this and how to correct it?
>> 
>> Thanks,
>> 
>> Dhanas
>> 
>> 
>> On Jan 11, 2012, at 9:44 PM, Michael Bieri wrote:
>> 
>>> Hi Dhanas
>>> 
>>> Each result is also saved in a csv file, which you can open is Excel. 
>>> If you are looking for the summary of your results, you can find them 
>>> in Exp_x_Model_selection.csv or Global_fit_Model_Selection.csv.. If 
>>> you are looking for a summary of R2eff per residue, you will have to 
>>> activate the creation of R2eff plots in the NESSY settings.
>>> 
>>> Cheers
>>> Michael
>>> 
>>> 
>>> 
>>> Am 12.01.2012 10:37, schrieb Dhanasekaran Muthu:
>>>> Hi Michael,
>>>> 
>>>> Thanks for your reply. In fact I have repeated some of the 
>>>> experiments. I will try to run with that data.
>>>> 
>>>> I have recently encountered another problem with Windows version. I 
>>>> get "an unhandled exception occured" message when I try to load the 
>>>> PDB file. It is not a problem in the Mac version.  So I create the 
>>>> state file (.nessy) in mac version and use that in Windows version 
>>>> to do the calculation.
>>>> 
>>>> Is it possible to export the summary of R2eff into a excel sheet or 
>>>> a text file?
>>>> 
>>>> Thanks,
>>>> 
>>>> Dhanas
>>>> 
>>>> On Jan 10, 2012, at 5:58 PM, Michael Bieri wrote:
>>>> 
>>>>> Hi Dhanas
>>>>> 
>>>>> I have reanalyzed your data and got the same error. If I turn on 
>>>>> Global Fit in the models settings, it works fine. This seems to 
>>>>> have something to do with the error of your data. As far as I can 
>>>>> see, you have never repeated any experiment. For appropriate error 
>>>>> estimation of your NMR data, at least one experiment should be 
>>>>> recorded in doublicate. For any reason, individual fit mode has 
>>>>> some problem with this and the global fit mode does not. I have to 
>>>>> dig in this. For the moment, you can select the global fit mode, 
>>>>> but I did not get any statistically significant exchange in your 
>>>>> data. This might be as you have no error of your data set. I 
>>>>> strongly recommend to perform at least one duplicate and record is 
>>>>> also on another field.
>>>>> 
>>>>> I hope this helped and feel free to ask any further question.
>>>>> 
>>>>> Cheers
>>>>> Michael
>>>>> 
>>>>> 
>>>>> Am 11.01.2012 10:21, schrieb Dhanasekaran Muthu:
>>>>>> Hi Michael,
>>>>>> 
>>>>>> The program works fine on Windows 7. In fact I used nessy.save 
>>>>>> file created from the mac version to run the calculation. I got 
>>>>>> the results. The x-axis range of the plot is very narrow (-0.0010 
>>>>>> to 0.0010) which is not correct. It should be 0 to 1000 Hz.  I 
>>>>>> have attached an ensemble .svg file for your reference. I do not 
>>>>>> know how to correct it. I am not sure I am setting the experiment 
>>>>>> right. I have also attached the .nessy for your reference. Any 
>>>>>> help will be very useful.
>>>>>> 
>>>>>> Thanks,
>>>>>> 
>>>>>> Dhanas
>>>>>> 
>>>>>> 
>>>>>> 
>>>>>> On Fri, Jan 6, 2012 at 4:00 AM, <[email protected] 
>>>>>> <mailto:[email protected]>> wrote:
>>>>>> 
>>>>>>    Send Nessy-users mailing list submissions to
>>>>>>    [email protected] <mailto:[email protected]>
>>>>>> 
>>>>>>    To subscribe or unsubscribe via the World Wide Web, visit
>>>>>>    https://mail.gna.org/listinfo/nessy-users
>>>>>>    or, via email, send a message with subject or body 'help' to
>>>>>>    [email protected] <mailto:[email protected]>
>>>>>> 
>>>>>>    You can reach the person managing the list at
>>>>>>    [email protected] <mailto:[email protected]>
>>>>>> 
>>>>>>    When replying, please edit your Subject line so it is more
>>>>>>    specific
>>>>>>    than "Re: Contents of Nessy-users digest..."
>>>>>> 
>>>>>> 
>>>>>>    Today's Topics:
>>>>>> 
>>>>>>      1. Re: NESSY problem with the mac machine (Dhanasekaran Muthu)
>>>>>> 
>>>>>> 
>>>>>>    ----------------------------------------------------------------------
>>>>>> 
>>>>>>    Message: 1
>>>>>>    Date: Thu, 5 Jan 2012 16:47:01 -0700
>>>>>>    From: Dhanasekaran Muthu <[email protected]
>>>>>>    <mailto:[email protected]>>
>>>>>>    Subject: Re: [Nessy-users] NESSY problem with the mac machine
>>>>>>    To: Michael Bieri <[email protected]
>>>>>>    <mailto:[email protected]>>
>>>>>>    Cc: [email protected] <mailto:[email protected]>
>>>>>>    Message-ID: <[email protected]
>>>>>>    <mailto:[email protected]>>
>>>>>>    Content-Type: text/plain; charset="iso-8859-1"
>>>>>> 
>>>>>>    Hi Michael,
>>>>>> 
>>>>>>    The Synthesis data creator pops up, nothing happens when I
>>>>>>    click the create and program freezes. I need to kill by
>>>>>>    shutting down the terminal window.
>>>>>> 
>>>>>>    I will try to install Ubuntu using virtual box on my Mac. I
>>>>>>    will inform you once I finish installing everything.
>>>>>> 
>>>>>>    Thanks,
>>>>>> 
>>>>>>    Dhanas
>>>>>> 
>>>>>> 
>>>>>>    On Jan 5, 2012, at 4:12 PM, Michael Bieri wrote:
>>>>>> 
>>>>>>> Hi Dhanas
>>>>>>> 
>>>>>>> Does the program freeze when you are pressing a button of
>>>>>>    the toolbar as well. There are some issues with dialogs on
>>>>>>    Mac. Does the Synthetis data creator pop up or dies it freeze
>>>>>>    immediately?
>>>>>>> 
>>>>>>> NESSY is intensively tested on Linux. If you want to make
>>>>>>    sure you get the full power of it, you can always install
>>>>>>    Linux (eg. Ubuntu and use the .deb version of NESSY) in a
>>>>>>    virtual box  (https://www.virtualbox.org/) on your Mac. This
>>>>>>    will slow down the analysis slightly, but Python programs work
>>>>>>    best on Linux Machines. Otherwise have a go on Windows.
>>>>>>> 
>>>>>>> But I realy would like to debug the Mac version. So any
>>>>>>    information will help.
>>>>>>> 
>>>>>>> Cheers
>>>>>>> Michael
>>>>>>> 
>>>>>>> Am 06.01.2012 09:43, schrieb Dhanasekaran Muthu:
>>>>>>>> 
>>>>>>>> Hi Michael,
>>>>>>>> 
>>>>>>>> Thanks for lightening fast reply. I did not expect that!
>>>>>>>> 
>>>>>>>> I think I used the binary method to install. I downloaded
>>>>>>    the zip file and just used the command ./nessy on the prompt.
>>>>>>    It opened the beautiful graphical interface. Then I loaded the
>>>>>>    peak intensity from Sparky data and run the experiment. The
>>>>>>    R2eff is calculated without any problem, but it does not
>>>>>>    proceed further, even if it is it hangs after the first residue.
>>>>>>>> 
>>>>>>>> I do not know what is the version, because About button is
>>>>>>    not working i.e. it does not do anything if I click. I have
>>>>>>    attached the screen shot in this mail. The Synthetic Data
>>>>>>    generator does not seem to work. I run that nothing happens. I
>>>>>>    am not sure it takes very long time or not.
>>>>>>>> 
>>>>>>>> BTW it is really a neat program. I really need this running
>>>>>>    and get some results. Is it fully tested on Windows machine?
>>>>>>    If so I can give a try.
>>>>>>>> 
>>>>>>>> I also liked your Relax program.  I have some questions
>>>>>>    regarding that also. I will ask about that in my next mail.
>>>>>>>> 
>>>>>>>> Thanks,
>>>>>>>> 
>>>>>>>> Dhanas Muthu
>>>>>>>> 
>>>>>>>> 
>>>>>>>> 
>>>>>>>> On Jan 5, 2012, at 3:16 PM, Michael Bieri wrote:
>>>>>>>> 
>>>>>>>>> Hi Dhanas
>>>>>>>>> 
>>>>>>>>> I have not fully tested NESSY on Mac, as I don't have one.
>>>>>>    Can you tell me which version of NESSY you are using and if
>>>>>>    you are using the compiled binary or the source code? Did you
>>>>>>    try to only use the first 2 models?
>>>>>>>>> 
>>>>>>>>> I will upload the Tutorial files shortly. In the mean
>>>>>>    time, you cane use the Synthetic Data generator (in Extras
>>>>>>    menu) to create a set of synthetic data in Sparky format. Then
>>>>>>    you can proceed as in the tutorial.
>>>>>>>>> 
>>>>>>>>> Cheers
>>>>>>>>> Michael
>>>>>>>>> 
>>>>>>>>> Am 06.01.2012 09:08, schrieb Dhanasekaran Muthu:
>>>>>>>>>> I am just following the thread initiated by Michael
>>>>>>    Osborne. I recently installed NESSY in my Mac machine running
>>>>>>    Lion.  When I try to run the calculations the program hangs
>>>>>>    after it starts the curve fitting. The R2eff values are
>>>>>>    calculated without any problem. For the fitting, I was trying
>>>>>>    to use only first 3 models. I am not sure Mike found any
>>>>>>    solution for his problem.   I would greatly appreciate if you
>>>>>>    have any answer for that.
>>>>>>>>>> 
>>>>>>>>>> Also, still the tutorial files are missing.  Can you
>>>>>>    provide the tutorial files as you have published the paper on
>>>>>>    NESSY, which will be really useful to familiarize with this
>>>>>>    nice program.
>>>>>>>>>> 
>>>>>>>>>> Thanks,
>>>>>>>>>> 
>>>>>>>>>> Dhanas Muthu
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