Cigarette Smoking Linked With Rectal Cancer Risk
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NEW YORK - Women who smoke appear to have nearly twice the risk of
developing rectal
cancer<http://www.lifescript.com/channels/healthy_living/News_Bites/cigarette_smoking_linked_with_rectal_cancer_risk.asp?utm_campaign=2007-12-11&utm_source=healthy-advantage&utm_medium=email&utm_content=todays-headlines_cigarette-smoking-lin&FromNL=1#>compared
with women who never smoked cigarettes, which supports the
accumulating evidence of this relationship, researchers report. The risk of
rectal cancer among women increased along with the number of cigarettes they
smoked per day, longer smoking duration, and older age at smoking cessation,
findings that also support evidence from earlierstudies, Dr. Electra D.
Paskett, and colleagues report in the Journal of the National Cancer
Institute.
"Smoking cessation and prevention are yet another way to prevent colorectal
cancer<http://www.lifescript.com/channels/healthy_living/News_Bites/cigarette_smoking_linked_with_rectal_cancer_risk.asp?utm_campaign=2007-12-11&utm_source=healthy-advantage&utm_medium=email&utm_content=todays-headlines_cigarette-smoking-lin&FromNL=1#>,"
Paskett, of Ohio State
University<http://www.lifescript.com/channels/healthy_living/News_Bites/cigarette_smoking_linked_with_rectal_cancer_risk.asp?utm_campaign=2007-12-11&utm_source=healthy-advantage&utm_medium=email&utm_content=todays-headlines_cigarette-smoking-lin&FromNL=1#>,
in Columbus, told Reuters Health. Women who choose to continue smoking
should receive regular screening for colorectal cancer, Paskett added.
The investigators looked at the incidence of colorectal cancer among more
than 140,000 women between 50 and 79 years old, who participated in Women's
Health Initiative, a long-term observational study.
Of these women, 51 percent reported never smoking, 42 percent were past
smokers, and 7 percent were current smokers.
Over 7.8 years, on average, 1,242 of the women developed invasive colorectal
cancer, the researchers found. Of these cancers, 176 wererectal cancer.
Compared with women who never smoked, current smokers were 95 percent more
likely to develop rectal cancer, but did not have an increased risk of colon
cancer<http://www.lifescript.com/channels/healthy_living/News_Bites/cigarette_smoking_linked_with_rectal_cancer_risk.asp?utm_campaign=2007-12-11&utm_source=healthy-advantage&utm_medium=email&utm_content=todays-headlines_cigarette-smoking-lin&FromNL=1#>.
These relationships held after the researchers adjusted the data to account
for other factors known to influence colorectal cancer development.
These factors included age, ethnicity, family history, physical
activity; nonsteroidal
anti-inflammatory
drugs<http://www.lifescript.com/channels/healthy_living/News_Bites/cigarette_smoking_linked_with_rectal_cancer_risk.asp?utm_campaign=2007-12-11&utm_source=healthy-advantage&utm_medium=email&utm_content=todays-headlines_cigarette-smoking-lin&FromNL=1#>,
hormone
therapy<http://www.lifescript.com/channels/healthy_living/News_Bites/cigarette_smoking_linked_with_rectal_cancer_risk.asp?utm_campaign=2007-12-11&utm_source=healthy-advantage&utm_medium=email&utm_content=todays-headlines_cigarette-smoking-lin&FromNL=1#>;
alcohol use; dietary intake of calcium, fiber, fat and red meat; waist
circumference; and the women's history of diabetes.
A similar analysis did not associate passive smoking with an increased risk
for colorectal cancer, the investigators note.
As mentioned, these findings provide another reason to encourage smoking
prevention and cessation programs, the investigators conclude.
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