[NMusers] Why population PK approach is good for pooling data compared to Classical statistical analysis?

[ayyappa . 5 . chaturvedula]

Dear Group,

Could anybody explain or direct me to some literature why population PK 
approach allows us to pool data from different studies but no classical 
statistical analysis? 

Regards,
Ayyappa Chaturvedula
GlaxoSmithKline
1500 Littleton Road,
Parsippany, NJ 07054
Ph:9738892200