Nyashadzaishe, UK and I believe WHO growth charts are derived using LMS method which you can do in R - look for papers by TJ Cole. I also suspect you might get a response from a certain NHG Holford telling you to look at his NONMEM method: Paediatr Anaesth. 2011 Mar;21(3):309-15 - I have only skimmed this paper but I think the introduction gives a review of possible methods. BW, Joe
________________________________ From: owner-nmus...@globomaxnm.com [owner-nmus...@globomaxnm.com] On Behalf Of nyashadzaishe mafirakureva [nmafirakur...@gmail.com] Sent: 17 February 2011 13:24 To: nmusers@globomaxnm.com Subject: [NMusers] Growth Curve Modelling I am trying to model growth in children (1-20 years) with a particular disease condition in NONMEM, R or any other software. There seem to be a lack of concensus in literature on the functions (models) one can use. I am therefore looking for some pointers from anyone who could have worked on something similar before. Thank you -- Nyashadzaishe Mafirakureva ******************************************************************************************************************** This message may contain confidential information. If you are not the intended recipient please inform the sender that you have received the message in error before deleting it. Please do not disclose, copy or distribute information in this e-mail or take any action in reliance on its contents: to do so is strictly prohibited and may be unlawful. Thank you for your co-operation. NHSmail is the secure email and directory service available for all NHS staff in England and Scotland NHSmail is approved for exchanging patient data and other sensitive information with NHSmail and GSi recipients NHSmail provides an email address for your career in the NHS and can be accessed anywhere For more information and to find out how you can switch, visit www.connectingforhealth.nhs.uk/nhsmail ********************************************************************************************************************