Alison Boeckmann will attempt to install El Capitan on her Mac to determine 
what needs to be done.

Meanwhile, did you also update to the corresponding version of Xcode?

Robert J. Bauer, Ph.D.
Vice President, Pharmacometrics R&D
ICON Early Phase
Office: (215) 616-6428
Mobile: (925) 286-0769
[email protected]<mailto:[email protected]>
www.iconplc.com<http://www.iconplc.com>

From: [email protected] [mailto:[email protected]] On 
Behalf Of Tingjie Guo
Sent: Wednesday, October 21, 2015 9:04 AM
To: [email protected]
Subject: [NMusers] NONMEM installation error on OS X EI Capitan

Dear NMusers,

Recently I upgraded my Mac to OS X EI Capitan, yet this broke the installation 
of NONMEM like last year when I upgraded my Mac to Yosemite. I tried to 
reinstall NONMEM but with error. The following is how I did.

1) I prefer to take gcc/gfortran binaries from High Performance Computing for 
Mac OS X (http://hpc.sourceforge.net/<http://hpc.sourceforge.net/>). The latest 
gcc/gfortran 5.2 for EI Capitan were installed by command sudo tar -xvf 
gcc-5.2-bin.tar.gz -C / and sudo tar -xvf gfortran-5.2-bin.tar.gz -C /. This 
step was successful. I tested in terminal by running gfortran -v, it showed the 
right returns.

2) Then I tried to install NONMEM by command sudo /bin/bash setup73 [NONMEM 
source path] [Target path] gfortran y /opt/local/bin/ar same rec i unzip 
nonmem73e.zip<http://nonmem73e.zip> nonmem73r.zip<http://nonmem73r.zip>.

When it came to Step 10. Build NONMEM archive nm/nonmem.a, it showed like this:

Step 10. Build NONMEM archive nm/nonmem.a
NMTRAN.exe was not created

Please look for error messages in /opt/nm73/compilemsgs.txt and 
/opt/nm73/finishmsgs.txt
Installation Aborted

The attachments are compilemsgs.txt and finishmsgs.txt. I'm not very clear 
about the error messages, it seems that there is still something wrong with 
gcc/gfortran. There is nothing different in setting gcc/gfortran this time 
compare to before. So I have no idea about this issue.
Is there any experience about this problem? And any advice would be appreciated.

Thanks!
Tingjie

Tingjie Guo
M.S. Candidate
Peking University/Pfizer Pharmacometrics Education Centre
Department of Pharmaceutics, School of Pharmaceutical Sciences
Peking University, Beijing, China
<br /><br />
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