Workshop on Convolution-based modeling approach March 11-13, 2019: Fort Lauderdale, FL (USA)
This three-day, hands-on course provides a working knowledge of the theories and application of the state-of-the-art convolution-based modeling approach to characterize complex PK profiles, to establish in-vitro in-vivo correlation (IVIVC) and to optimize ER and LAI formulation development using the exposure-response relationship. Supportive material for the workshop can be found in our recent paper published in the CPT Pharmacometrics Syst Pharmacol journal: https://www.ncbi.nlm.nih.gov/pubmed/30659771 Interactive and real life examples, taken from actual industry experience using R and NONMEM will be presented and discussed in the hands-on sections to illustrate how to deal with delayed, multiple peaks and time dependent absorption process, how to establishing a Level A IVIVC using a model-informed approach and how to develop optimized formulations with an in-vivo drug release suitable to maximize the clinical benefit of a treatment. Who Should Attend? The workshop is designed for pharmaceutical scientists, pharmacologists, physicians and other scientists involved in drug development wishing to learn and apply pharmacometrics as innovative decision supporting tool for accelerating drug discovery and development. What Will You Learn? Upon completion of this course, you should have a solid understanding of how to implement convolution-based models using NONMEM, how to implement IVIVC using NONMEM, how to simulate drug exposure as a function of the modified in-vivo delayed and time dependent drug release properties of ER and LAI formulations using R, and how to optimize the properties of ER and LAI formulations for maximizing the clinical benefit of a treatment. Venue Fort Lauderdale Marriott Harbor Beach Resort & Spa, 3030 Holiday Drive, Fort Lauderdale, FL 33316 USA <https://www.marriott.com/hotels/travel/fllsb-fort-lauderdale-marriott-harbo r-beach-resort-and-spa/> https://www.marriott.com/hotels/travel/fllsb-fort-lauderdale-marriott-harbor -beach-resort-and-spa/ For additional information, visit our website: <https://www.pharmacometrica.com/next-workshop> https://www.pharmacometrica.com/next-workshop Roberto Gomeni, PhD. Pharmacometrica Longcol, 12270 La Fouillade (France) E-mail: <mailto:roberto.gom...@pharmacometrica.com> roberto.gom...@pharmacometrica.com www.pharmacometrica.com <http://www.pharmacometrica.com/> Next workshops on pharmacometrics: <https://www.pharmacometrica.com/next-workshop> https://www.pharmacometrica.com/next-workshop
